Prognostic value of ventricular arrhythmias in hypertensive patients

Galinier, Michel; Bălănescu, Şerban Mihai; Fourcade, J; Dorobanțu, Maria; Massabuau, P; Dongay, Bruno; Cabrol, Philippe; Jm, Fauvel; Bounhoure, Jean-Paul

doi:10.1097/00004872-199715110-00044

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“… 3 , 13 The underlying mechanisms of arrhythmogenicity in hypertension and DM include LVH, myocardial ischemia, impaired left ventricular function, and left atrial enlargement, among other factors. 6 , 16…”

Section: Discussionmentioning

confidence: 99%

“… 3 , 4 Type 2 diabetes mellitus (T2DM) and hypertensive left ventricular hypertrophy (LVH) are associated with increased risk of arrhythmias and mortality. 5 , 6 Yet there are very limited published studies in Nigeria on the use of 24 hour Holter ECG in the arrhythmic evaluation of hypertensive and diabetic patients. 7 – 9 In this study, 7 it was observed that LVH increased arrhythmias, and multivalvular regurgitations predispose to greater supra-ventricular tachycardia and complex ventricular arrhythmias, especially in hypertensive heart failure (HHF).…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of the indications and arrhythmic patterns of 24 hour Holter electrocardiography among hypertensive and diabetic patients seen at OAUTHC, Ile-Ife Nigeria

Adebayo¹,

Ikwu²,

Balogun³

et al. 2014

DMSO

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BackgroundThere are very limited published studies in Nigeria on the use of 24 hour Holter electrocardiogram (Holter ECG) in the arrhythmic evaluation of hypertensive and diabetic patients.ObjectiveTo evaluate indications, arrhythmic pattern of Holter ECG, and heart rate variability (HRV) among patients with hypertensive heart disease (HHD) with or without heart failure and type 2 diabetes mellitus (T2DM) seen in our cardiac care unit.MethodsSeventy-nine patients (32 males and 47 females) were studied consecutively over a year using Schiller type (MT-101) Holter ECG machine.ResultsOut of the 79 patients, 17 (21.5%) had HHD without heart failure, 33 (41.8%) had HHD with hypertensive heart failure (HHF), while 29 (36.7%) were T2DM patients. The mean (standard deviation) ages of HHD without heart failure, HHF and T2DM patients were 59.65 (±14.38), 65.15 (±14.30), and 54.66 (±8.88) respectively. The commonest indication for Holter ECG was palpitation (38%), followed by syncope (20.3%). Premature ventricular contraction was the commonest arrhythmic pattern among the 79 patients, especially among HHF patients. The HRV using standard deviation of all normal-normal intervals was significantly reduced in T2DM patients (81.03±26.33, confidence interval [CI] =71.02–91.05) compared to the HHD without heart failure (119.65±29.86, CI =104.30–135.00) and HHF (107.03±62.50, CI =84.00–129.19). There was a negative correlation between the duration of T2DM and HRV (r=−0.613).ConclusionPalpitation was the commonest Holter ECG indication and premature ventricular contractions were the commonest arrhythmic pattern among our patients. HRV was reduced in T2DM patients compared with hypertensive patients.

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Section: Discussionmentioning

confidence: 99%