Programa de detección de neoplasias colorrectales en población mayor de 50 años

López-Köstner, Francisco; Kronber, Udo; Zárate, Alejandro; Wielandt, Ana María; Pinto, Eliana; Suazo, Cristóbal; Orellana, Paulina; Avendaño, Rodolfo; Bresky, Gustavo; Castillo, M.; Lubascher, Jaime; Karelovic, Stanko; Ross, Marcelo; Ocares, Misael; Riquelme, F.; Contreras, Luis; Vargas, Blanca; Cortés, Miguel

doi:10.4067/s0034-98872012000300001

Cited by 17 publications

(8 citation statements)

References 21 publications

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“…Studies have shown that FIT screening is superior to G-FOBT in both aspects[20,47]. The overall results showed that the highest participation rates were obtained in programs using FIT.…”

Section: Comparison Of the Results Of Several Crc Screening Programsmentioning

confidence: 98%

Colorectal cancer population screening programs worldwide in 2016: An update

Navarro

Nicolas

Ferrández

et al. 2017

WJG

473

364

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Colorectal cancer (CRC) is the third most commonly diagnosed cancer in the world. The incidence and mortality show wide geographical variations. Screening is recommended to reduce both incidence and mortality. However, there are significant differences among studies in implementation strategies and detection. This review aimed to present the results and strategies of different screening programs worldwide. We reviewed the literature on national and international screening programs published in PubMed, on web pages, and in clinical guidelines. CRC Screening programs are currently underway in most European countries, Canada, specific regions in North and South America, Asia, and Oceania. The most extensive screening strategies were based on fecal occult blood testing, and more recently, the fecal immunochemical test (FIT). Participation in screening has varied greatly among different programs. The Netherlands showed the highest participation rate (68.2%) and some areas of Canada showed the lowest (16%). Participation rates were highest among women and in programs that used the FIT test. Men exhibited the greatest number of positive results. The FIT test has been the most widely used screening program worldwide. The advent of this test has increased participation rates and the detection of positive results. Core tip: Colorectal cancer is the third most commonly diagnosed cancer worldwide. The incidence and mortality show wide geographical variations across the world. Screening is recommended to reduce both, however, there are significant differences among studies in implementation strategies and detection. This review aimed to present the results and strategies of different screening programs worldwide.

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“…Studies have shown that FIT screening is superior to G-FOBT in both aspects[20,47]. The overall results showed that the highest participation rates were obtained in programs using FIT.…”

Section: Comparison Of the Results Of Several Crc Screening Programsmentioning

confidence: 98%

Colorectal cancer population screening programs worldwide in 2016: An update

Navarro

Nicolas

Ferrández

et al. 2017

WJG

473

364

View full text Add to dashboard Cite

show abstract

“…FIT testing was used and only patients older than 50 were screened. 76 There are no organized screening programs in any African country. In South Africa, there is a lack of facilities in the rural areas and in the mid-2010s a pilot study using a mobile screening facility was found to improve survival.…”

Section: Colorectal Cancer Preventionmentioning

confidence: 99%

<p>Colorectal Cancer Genetics, Incidence and Risk Factors: In Search for Targeted Therapies</p>

Hull¹,

Francies²,

Oyomno³

et al. 2020

CMAR

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Each year, colorectal cancers (CRCs) affect over a quarter of a million people. The risk of developing CRC in industrialized nations is approximately 5%. When the disease is localised, treatment success rates range from 70-90%; however, advanced CRC has a high mortality rate, consistently ranking in the top three causes of cancer-related deaths. There is a large geographic difference in global distribution, and CRC is predominantly associated with developed countries and a Western lifestyle and diet. As such, the developed world accounts for more than 63% of all cases of CRC. Geographic variations also predict cancer outcomes, which differ between racial and ethnic groups. This variation is due to inequalities in wealth, differences in the exposure to risk factors and barriers to high-quality cancer prevention, early detection and treatment. The aim of this paper was to review CRC in lowand middle-income countries such as South Africa, India, Brazil and China, and compare them with high-income countries such as the United States of America and the United Kingdom. It is important to note that these economically less developed countries, with historically low CRC rates, are experiencing an increased frequency of CRC. The review also discusses biological markers and genetic pathways involved in the development of colorectal cancer. Genes known to be responsible for the most common forms of inherited CRCs have also been identified but more remain to be identified. This would provide more candidate genes to be added to known biomarkers. CRC burden can be controlled through the widespread application of existing knowledge, such as reduced smoking habits, vaccination, early detection and promoting physical activity, accompanied by a healthy diet. An increased understanding of the molecular mechanisms and events underlying colorectal carcinogenesis will enable the development of new targets and therapeutic drugs.

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“…De estos, 58,6% se realizó la colonoscopía completa, detectando pólipos en 40,2%. Los adenomas fueron resecados y 1,1% correspondió a cáncer en etapa localizada 27 . Luego se generó un segundo reporte que consideró una mejoría en el diseño de los protocolos, así como realización de capacitaciones endoscópicas, de anatomía patológica y de biología molecular, bajo el alero del Programa de Prevención de Neoplasias Colorrectales (PRENEC) que es una alianza entre Universidad Médica y Dental de Tokyo (UDTM), Clínica Las Condes (CLC) y MINSAL 28,29 .…”

Section: Diagnósticounclassified

Situación actual del cáncer de colon en Chile: una mirada traslacional

et al. 2020

Self Cite

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Seventy-five percent of colorectal cancers are sporadic, 20% have a family component (first or second-degree relatives with CRC) and 5% have a hereditary predisposition with a Mendelian pattern. The epidemiological evolution in the recent years in Chile has a worrisome evolution and the treatment costs of advanced stages are a burden for the healthcare system. We herein highlight the main Chilean medical and scientific contributions on the pathogenesis, early diagnosis, and treatment of CRC, which lead to its better understanding, and therefore better management, based on local evidence.

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Programa de detección de neoplasias colorrectales en población mayor de 50 años

Abstract: This program allowed the early detection of an important number of high risk colon lesions, and all patients with CCR were diagnosed at early stages.

Cited by 17 publications

References 21 publications

Colorectal cancer population screening programs worldwide in 2016: An update

Colorectal cancer population screening programs worldwide in 2016: An update

<p>Colorectal Cancer Genetics, Incidence and Risk Factors: In Search for Targeted Therapies</p>

Situación actual del cáncer de colon en Chile: una mirada traslacional

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