Progressive Multifocal Leukoencephalopathy with Immune Reconstitution Inflammatory Syndrome (PML-IRIS): Two Case Reports of Successful Treatment with Mefloquine and a Review of the Literature

The Human Immunodeficiency Virus (HIV) Epidemic in Singapore—Where Are We Now, and Can We “Get to Zero”?

“…For patients on appropriate cART, there are still the pitfalls of unexpected drug-drug interactions including efavirenz which is a component of most fi rst-line regimens (Lee et al) 16 as well as the potential of immune reconstitution infl ammatory syndrome (Young et al). 17 Even as we increase our armamentarium of HIV prevention, diagnostic and treatment tools, HIV-related stigma and discrimination continue to act as potent barriers to effective responses. Fear of stigma and discrimination negatively impact people's will to be tested or to seek medical care, as illustrated by Dr Ng's article.…”