Prolapsing mitral valve leaflet syndrome. A spectrum that includes cleft posterior mitral valve

Abstract

Two patients with a prolapse and cleft posterior mitral leaflet were studied. The first case had an associated ostium secundum type atrial septal defect. In both cases, the pansystolic regurgitation of contrast material during angiography corresponded to the pansystolic configuration of the murmur. In each instance, the systolic murmurs displayed a late systolic accentuation during the maximal prolapse of the mitral valve. The echocardiographic studies demonstrated only a late systolic prolapse which in both patients corresponded angiocardiographically to the maximum buckling of the pansystolic prolapse. Echocardiographic and angiocardiographic features of cleft posterior mitral valve leaflet are discussed.

Mitral valve cleft associated with secundum atrial septal defect: case report and review of the literature

“…It is of interest that an electrocardiogram typical of an ostium primum syndrome, such as prolonged P-R interval, left axis deviation, and counter clock-wise rotation of the frontal QRS loop, can also occur in the secundum type ASD [2]. Among 16 articles that have been reported since 1960, a total of 42 cases were involved [1][2][3][5][6][7][8][9][10][11][12][13][14][15][16][17]. Four cases in the report by Liebman and Nadas [5] were atrioventricular valve cleft associated with secundum ASD.…”