Prolonged cholestasis following hepatitis a virus infection: Revisiting the role of steroids

Saboo, Ashwin Rajendra; Vijaykumar, Ramaa; Save, Sushma; Bavdekar, Sandeep B

doi:10.4103/0974-777x.100588

Cited by 13 publications

(3 citation statements)

References 7 publications

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“…135,136 Prolonged cholestasis has been observed in 4.7% of patients, and may be predicted by pre-existing chronic HBV infection, prolonged PT, and higher total bilirubin levels. 68 There are several reports about cholestatic hepatitis A in childhood [137][138][139][140] or adolescence. 141 Prolonged cholestasis is the most common atypical manifestation in childhood.…”

Section: Prolonged Cholestasismentioning

confidence: 99%

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Recent advances in hepatitis A virus research and clinical practice guidelines for hepatitis A virus infection in Japan

Kanda,

Sasaki‐Tanaka,

Ishii

et al. 2023

Hepatology Research

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In 2018, there was a hepatitis A outbreak in Japan, and hepatitis A virus (HAV) infection is considered a sexually transmitted disease. In general, patients with hepatitis A should be given attention, and this disease should be prevented more than ever. The Japan Agency for Medical Research and Development (AMED) Hepatitis A and E viruses (HAV and HEV) Study Group has worked on the project to create “Recent Advances in Hepatitis A Virus (HAV) Research and Clinical Practice Guidelines for HAV Infection in Japan”. The group consists of expert hepatologists and virologists who gathered at virtual meeting on August 5, 2023. Data about the pathogenesis, infection routes, diagnosis, complications, several factors for the severities, vaccination, and current and future treatments for hepatitis A were discussed and debated for a draft version. The participants assessed the quality of cited studies. The finalized recommendations are presented in this review. The recent advances in HAV research and clinical practice for HAV infection in Japan, have been reviewed by the AMED HAV and HEV Study Group.

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Section: Prolonged Cholestasismentioning

confidence: 99%

“…There are several reports about cholestatic hepatitis A in childhood 137–140 or adolescence 141 . Prolonged cholestasis is the most common atypical manifestation in childhood 142 .…”

Section: Consensus Statements and Recommendationsmentioning

confidence: 99%

Recent advances in hepatitis A virus research and clinical practice guidelines for hepatitis A virus infection in Japan

Kanda,

Sasaki‐Tanaka,

Ishii

et al. 2023

Hepatology Research

View full text Add to dashboard Cite

show abstract

“…Cholestatic hepatitis is one of very rare manifestations of acute HBV infection, but when develop it leads to prolonged hospital stay and increased medical expenses 5 . Rapid improvement of the clinical symptoms and signs have been reported in patients with cholestatic hepatitis A (HAV) after use of corticosteroid 6 . We here report a case of cholestatic hepatitis due to acute HBV infection and rapid improvement of symptoms with oral prednisolone.…”

Section: Introductionmentioning

confidence: 99%

Successful Treatment of Severely Cholestatic Acute Hepatitis B With Oral Corticosteroid

Mallick

Nath

Praharaj

et al. 2020

ABCD, arq. bras. cir. dig.

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Need for recognizing atypical manifestations of childhood sporadic acute viral hepatitis warranting differences in management

et al. 2018

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Prolonged cholestasis following hepatitis a virus infection: Revisiting the role of steroids

Cited by 13 publications

References 7 publications

Recent advances in hepatitis A virus research and clinical practice guidelines for hepatitis A virus infection in Japan

Recent advances in hepatitis A virus research and clinical practice guidelines for hepatitis A virus infection in Japan

Successful Treatment of Severely Cholestatic Acute Hepatitis B With Oral Corticosteroid

Need for recognizing atypical manifestations of childhood sporadic acute viral hepatitis warranting differences in management

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