Prolonged Extracorporeal Membrane Oxygenation Support In a Patient with Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome-associated Fulminant Myocarditis – A Case Report and Literature Review

Seree-aphinan, Chutima; Assanangkornchai, Nawaporn; Nilmoje, Thanapon

doi:10.17925/hi.2020.14.2.112

Heart International

2020

DOI: 10.17925/hi.2020.14.2.112

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Prolonged Extracorporeal Membrane Oxygenation Support In a Patient with Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome-associated Fulminant Myocarditis – A Case Report and Literature Review

Chutima Seree-aphinan¹,

Nawaporn Assanangkornchai²,

Thanapon Nilmoje³

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2024

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Novel Treatment for Pre-XDR Tuberculosis Linked to a Lethal Case of Acute Myocarditis

Kotoulas,

Poulios,

Chasapidou

et al. 2024

Diagnostics

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The management of resistant tuberculosis (tb) can be extremely difficult, especially in case of novel unpredicted complications. In this report, we present a case of a 48-year-old patient with pre-extensively drug-resistant (XDR) tb who received a treatment regimen including pretomanid, bedaquiline, linezolid, cycloserine, and amikacin and died due to myocarditis. Acquired resistance to first- and second-line drugs developed due to previous poor adherence to medication. The clinical presentation of the patient, along with her initial ultrasonographical, electrocardiogram (ECG), and laboratory examinations, were typical for acute myocarditis; however, the patient was considered unstable, and further investigations, including magnetic resonance imaging (MRI), pericardiocentesis, and endomyocardial biopsy were not performed. To our knowledge, this is the first case of myocarditis in such a patient, the clinical features of which raised a high suspicion of drug induction that could be attributed to the treatment regimen that was administered. Clinicians who manage cases of drug-resistant tb should be aware of this newly reported, potentially lethal, adverse event.

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Novel Treatment for Pre-XDR Tuberculosis Linked to a Lethal Case of Acute Myocarditis

Kotoulas,

Poulios,

Chasapidou

et al. 2024

Diagnostics

View full text Add to dashboard Cite

show abstract

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Prolonged Extracorporeal Membrane Oxygenation Support In a Patient with Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome-associated Fulminant Myocarditis – A Case Report and Literature Review

Cited by 1 publication

References 50 publications

Novel Treatment for Pre-XDR Tuberculosis Linked to a Lethal Case of Acute Myocarditis

Novel Treatment for Pre-XDR Tuberculosis Linked to a Lethal Case of Acute Myocarditis

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