Prolonged space flight: Adverse health effects and treatment options with medicinal plants and natural products

Abstract

Exposure to zero gravity causes many physiological changes which may result to affect the health of people involved in space travel. The current review summarizes current knowledge on the start and progression of space motion sickness, bone loss, muscle loss, cardiovascular disorders, respiratory problems, and neuronal and hormonal problems. Around 70% of astronauts suffer from space adaption syndrome, fluid changes, and head motions. It has also been suggested that otolith asymmetries and Coriolis cross-coupling stimulation are the main causes of space motion sickness. The findings reveal that space flight directly affects the body's normal functioning. Despite an intense training routine, a study of historical data from piloted flights discovered that slow degradation of bone and muscle tissue, along with fluid losses, can eventually lead to kidney stones, musculoskeletal problems, bone fractures, and even problems with other organs of the body. Due to such problems focus is given to curing these problems associated with space travel. Medicines that are used in space and medicinal plants like Spirulina, and Ginseng that are of use for the treatment of these problems associated with space travel are discussed along with the treatment options available for such problems in space and the cautions that must be followed. Also, the herbal medication that can be used in outer space is taken into account. The findings of this study state the necessary precaution that needs to be taken by astronauts in outer space and also provides information for future research to be done on solving these problems.

<strong>Gene-Edited Medicinal ‘Superplants’: Advancements for Prolonged Space Travel</strong>

“…The adverse physiological effects of extended space travel are highly variable and continue to be an obstacle in carrying out missions (Bhuyan et al, 2023). There is a plethora of health issues involved, including microgravity, bone density loss, impaired gut microbiota, and central fluid shift (Simanonok and Charles, 1994;Turroni et al, 2020;Bhuyan et al, 2023) Longer space travel invariably leads to rising health concerns that can be addressed using medications. However, storing copious amounts of pills and vitamins for unpredictable health concerns is not practical due to limited storage space.…”