Prolonged Survival for Choroid Plexus Carcinoma with Oncocytic Changes: A Case Report

Eppinger, Melissa Ann; Berman, Casey Melissa; Halpern, Steven; Mazzola, Catherine A.

doi:10.4172/2472-100x.1000107

Cited by 3 publications

(2 citation statements)

References 18 publications

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“…La resección total es el objetivo principal, sin embargo, esto se logra en sólo 40-50% de los casos. Varios estudios comparan los resultados de la resección total frente a la parcial, estableciendo la resección total como el mejor tratamiento posible (16) . Hoy en día, la resección total es el mayor factor predictivo de supervivencia.…”

Section: Discussionunclassified

Carcinoma de plexo coroideo en paciente pediátrico: Reporte de caso

Andino

Chávez

García³

2020

Act Ped Hond

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El carcinoma de plexo coroideo se considera dentro de los tumores del cerebro como uno de los más infrecuentes, presentándose principalmente en la población pediátrica con mayor incidencia en hombres. Las principales manifestaciones clínicas son secundarias a la obstrucción del flujo de líquido cefalorraquídeo. Dentro de los estudios de imagen que se pueden emplear para realizar el diagnóstico están la tomografía computarizada y la resonancia magnética sin embargo el diagnóstico definitivo es el estudio anatomopatológico. Presentamos el caso clínico de un niño de 13 años de edad que acudió a la emergencia de pediatría del Hospital Mario Catarino Rivas por cefalea de dos meses de evolución que posteriormente presentó alteración de la marcha y hemiparesia derecha. El principal objetivo de tratamiento es la resección total sin embargo no se logra en todos los casos. Se ha propuesto el uso de quimioterapia adyuvante con o sin radiación, sin embargo, aún no se ha estandarizado este enfoque.

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Section: Discussionunclassified

Carcinoma de plexo coroideo en paciente pediátrico: Reporte de caso

Andino

Chávez

García³

2020

Act Ped Hond

View full text Add to dashboard Cite

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“…2013, and mandibular salivary gland (Brocks et al 2008 ). Oncocytic tumours are a rare entity in cats compared to humans (Coburn et al 2007 ) and include examples in proliferative choroid plexus lesions (Louis et al 2007, Sav et al 2010, Eppinger et al 2016.…”

Section: Discussionmentioning

confidence: 99%

Surgical removal of a choroid plexus oncocytoma in an adult cat

Cossic

Silver²,

Kent

et al. 2017

J of Small Animal Practice

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An 11-year-old male castrated domestic shorthair cat presented with left central vestibular dysfunction. Magnetic resonance imaging of the brain revealed a large, extra-parenchymal, strongly contrast-enhancing mass at the level of the left cerebellopontine angle and compressing the cerebellum and brainstem. The mass was surgically excised via left rostral and sub-tentorial craniectomies and histopathology revealed an epithelial neoplasm composed of anastomosing cords of neoplastic cells that contained large amounts of finely granular hypereosinophilic cytoplasm and round nuclei. The cytoplasmic granules were variably positive with periodic acid-Schiff and modified Gomori trichrome. Immunohistochemical staining with anti-cytokeratin AE1/AE3 was diffusely positive. Electron microscopy revealed neoplastic cells that were full of electron-dense organelles consistent with mitochondria. This is the first case of a choroid plexus oncocytoma in the central nervous system of any domestic animal species and highlights the role of successful surgical intervention in extra-parenchymal neoplasia in the central nervous system.

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Nursing Observation on the Clinical Efficacy and Toxicity of Lobaplatin Compared with Cisplatin in the Treatment of Locally Advanced Hypopharyngeal Carcinoma Based on Intelligent CT Imaging

Yang

et al. 2021

Journal of Healthcare Engineering

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With the acceleration of people’s life rhythm, the incidence of hypopharyngeal cancer has generally increased. This study mainly explores the clinical efficacy and toxicity of lobaplatin compared with cisplatin in the treatment of locally advanced hypopharyngeal carcinoma based on intelligent CT imaging. Group A received lobaplatin combined with docetaxel induction chemotherapy for 2 cycles after cisplatin combined with intensity-modulated radiotherapy. Lobaplatin was added to the patient, then, 200 ml of 5% glucose was added, and the patient was injected intravenously for 1.8 hours. After 2 cycles of induction chemotherapy, simultaneous lobaplatin chemotherapy was performed every week for 5 weeks (10 mg/week), and the efficacy was evaluated after 4 consecutive courses of treatment. Group B received cisplatin combined with docetaxel induction chemotherapy after 2 cycles of cisplatin combined with intensity-modulated radiotherapy. Group C was the control group and was not treated with cisplatin or docetaxel. Stomach protection treatment was given in time throughout the treatment process. All patients underwent normal CT (NCCT) and enhanced CT (CECT) examinations before treatment. We extracted 5 mm plain scan CTQNCCT and enhanced CT (CECT) digital DICOM images from the PACS system for omics feature selection. Toxic and side effects are rated in different degrees according to the evaluation criteria of the National Cancer Institute (NCD) common adverse events. Blood routine and liver and kidney function tests were checked every week, and the medication was stopped immediately if there is a serious reaction. In addition, in vitro cell culture was set up to test the inhibitory effect of cisplatin and lobaplatin on the proliferation of cancer cells. The incidence of digestive tract reaction was 13.0% in the A plan group and 58.3% in the B plan group. The A group was lower than the B group, and the difference was statistically significant ( P = 0.001 < 0.05). Compared with cisplatin, lobaplatin has a milder gastrointestinal reaction, and there is no common hepatic and renal toxicity of cisplatin. This study is helpful to provide guidance for the clinical efficacy of locally advanced hypopharyngeal cancer treatment.

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Prolonged Survival for Choroid Plexus Carcinoma with Oncocytic Changes: A Case Report

Cited by 3 publications

References 18 publications

Carcinoma de plexo coroideo en paciente pediátrico: Reporte de caso

Carcinoma de plexo coroideo en paciente pediátrico: Reporte de caso

Surgical removal of a choroid plexus oncocytoma in an adult cat

Nursing Observation on the Clinical Efficacy and Toxicity of Lobaplatin Compared with Cisplatin in the Treatment of Locally Advanced Hypopharyngeal Carcinoma Based on Intelligent CT Imaging

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