Prompt gamma detection for range verification in proton therapy

122: Development of a Time-Of-Flight Compton Camera for Online Control of Ion Therapy

“…Several devices are under development over the world to detect secondary radiations, which are correlated to the dose deposited by incident ions. Compton cameras are in particular investigated for their potential high effi ciency to detect prompt gamma rays [1,2,3,4]. The present work aims at discussing the clinical applicability of a Compton camera design by means of Monte Carlo simulations for proton and carbon ion therapy.…”

Statistical analysis for discrimination of prompt gamma ray peak induced by high energy neutron: Monte Carlo simulation study

“…The peaks of the characteristic prompt gamma ray are demonstrated on a continuous energy spectrum. If the discrimination of the prompt gamma ray peak is applied to the non-destructive inspection, although the components of the target material were not previously identified, the target can be estimated without using a chemical component test or the destructive techniques [2][3][4][5]. Thus, this prompt gamma ray activation analysis (PGAA) method can be applied to detect explosives and drugs in an airport or a harbor [6,7].…”

Feasibility Study on an Application of Scintillation Fiber Imager to Realtime Range Monitoring System for Carbon Ion Therapy

“…PET range verification has been studied by several institutes [3,4], but it is basically post-irradiation verification and substantially difficult as a real time monitoring system. Prompt gamma verification is currently drawing many attentions, which utilizes slit camera system [5] or Compton cameras including electron tracking Compton cameras (ETCC) [6]. Possible another probe for realtime range verification is secondary charged particles like protons and helium ions escaped from the body.…”