Propensity score analysis of postoperative and oncological outcomes after surgical treatment for splenic flexure colon cancer

Abstract

The short and long-term outcomes between ERC, SLC, and LC are similar. SLC should be considered oncologically as appropiate as the other more extensive resections.

Comparison of extended right hemicolectomy, left hemicolectomy and segmental colectomy for splenic flexure colon cancer: a systematic review and meta‐analysis

“…Therefore, seven studies were eligible for this study. These included seven comparative observational studies [11][12][13][14][15][16][17]. Figure 1 demonstrates the literature search flow chart and Table 2 outlines the baseline characteristics of the included studies.…”

“…We performed a systematic literature review and metaanalysis to compare the outcomes of ERH, LH and SC in the surgical management of splenic flexure tumours. We identified seven observational studies [11][12][13][14][15][16][17] enrolling a total of 956 patients. The results of the analyses showed that there was no difference between the three techniques in terms of anastomotic leakage, total postoperative complications, R0 resection, severe complications, postoperative mortality, wound infection, pancreatic fistula, intra-abdominal abscesses, the need for reoperation, 5-year overall survival and 5-year disease-free survival.…”

“…Gravante 2016 [13] Martin Arevalo 2018 [11] Odermatt 2014 [14] de' Angelis 2016 [12] de' Angelis 2016 [12] de' Angelis 2020 [ Test for overall effect: Z = 0.89 (P = 0.37) Heterogeneity: Chi 2 = 3.15, df = 4 (P = 0.53); I 2 = 0% Test for overall effect: Z = 0.59 (P = 0.56) Heterogeneity: Tau 2 = 519.85; Chi 2 = 19.68, df = 4 (P = 0.0006); I 2 = 80% Gravante 2016 [13] Martin Arevalo 2018 [11] Odermatt 2014 [14] de' Angelis 2016 [12] de' Angelis 2020 [ [14] de' Angelis 2016 [12] de' Angelis 2020 [15] de' Angelis 2020 [15] de' Angelis 2020 [15] de' Angelis 2020 [15] Rega 2019 [16] Rega 2019 [16] Rega 2019 [16] Rega 2019 [16] Total ( Odermatt 2014 [14] Odermatt 2014 [14] Odermatt 2014 [14] de' Angelis 2016 [12] de' Angelis 2016 [12] de' Angelis 2016 [12] Gravante Odermatt 2014 [14] de' Angelis 2016 [12] de' Angelis 2016 [12] de' Angelis 2016 [12] de' Angelis 2016 [12] de' Angelis 2016 [ Odermatt 2014 [14] de' Angelis 2016 [12] de' Angelis 2016 [12] de' Angelis 2016 [12] de' Angelis 2020 [15] de' Angelis 2020 [15] de' Angelis 2020 [15] Rega Gravante 2016 …”

“…Heterogeneity: Tau 2 = 0.00; Chi 2 = 6.46, df = 3 (P = 0.09); I 2 = 54% [11] de' Angelis 2020 [15] de' Angelis 2020 [15] Rega de' Angelis 2020 [15] de' Angelis 2020 [15] Rega 2019 [16] Rega 2019 [16] Martin Arevalo 2018 [11] de' Angelis 2020 [15] Rega 2019 [16] Segmental colectomy versus left hemicolectomy Figure 5 highlights the results of analyses and outcome synthesis for the comparison of SC and LH.…”

Primary tumor resection improves prognosis of unresectable carcinomas of the transverse colon including flexures with liver metastasis: a preliminary population-based analysis

“…Due to the complexity of lymphatic drainage of the transverse colon including flexures [ 74 – 77 ], many surgeons preferred enlarged resection and extensive lymph node dissection. Some studies have answered yes to the adequacy of segmental colon dissection, suggesting that SCR could remove the same or less number of lymph nodes than LCR, but there was no difference in prognosis between the two groups [ 69 , 70 , 78 , 79 ]. Besides, SCR for transverse colon cancer was associated with less ileus but higher anastomotic leak rates and lower lymph node yields, and similar hospital stay [ 69 ].…”