“…Some studies have demonstrated the cytotoxic potential of antisera to adipocytes in vivo (Futter et al, 1992;Kestin et al, 1993) and in vitro (De clercq et al, 1997). There have been also some evidences that antibodies against various protein components of adipocyte plasma membranes could block the binding of various hormones to their receptors on the plasma membrane to interrupt the signal transduction, and/or to disturb the assembly of various transporters to the membrane to influence the substance transport across the membrane (Kaise et al, 1988;Oka et al, 1988;Ros et al, 1988;Suzuki et al, 1988). It was reported (De clercq et al, 1997) that the sizes of adipocytes became smaller when treated with antibody against porcine adipocyte plasma membrane.…”