Prophylaxis for deep vein thrombosis with aspirin or low molecular weight dextran in Korean patients undergoing total hip replacement;a randomized controlled trial

Low-Dose Aspirin Is Adequate for Venous Thromboembolism Prevention Following Total Joint Arthroplasty: A Systematic Review

“…Kim et al evaluated low-molecular-weight dextran, aspirin, and control groups as thromboprophylactic agents after THA. Their data suggested that low-molecular-weight dextran provided better DVT thromboprophylaxis after THA compared to the control group and furthermore did not find a significant difference in incidence of DVT between the aspirin and the control group [50]. However, this study only investigated 150 patients and their reported values of DVT prevalence are high compared to our data.…”

“…Although many studies have demonstrated the benefits of aspirin, other studies suggest that aspirin may be less effective than other prophylactic drugs [37,50,69,70]. A meta-analysis by Imperiale and Speroff [69] found no significant difference in incidence of PE or DVT between aspirin and control groups after THA, while lowmolecular-weight heparin (LMWH) with compression stockings was significantly more effective than the control.…”

“…However, this study only investigated 150 patients and their reported values of DVT prevalence are high compared to our data. Additionally, our systematic review only included symptomatic VTE, while Kim et al [50] included asymptomatic VTE diagnosed by contrast venography.…”

Systematic review and meta-analysis on the rate of postoperative venous thromboembolism in orthopaedic surgery in Asian patients without thromboprophylaxis

“…There appeared to be variation among ethnic groups and geographical locations in Asia, perhaps partly explaining the heterogeneity among studies. Some authors believe that the prevalence of VTE in Asia is increasing as a result of environmental change and Westernization of food 8,10,13,24,29 . The present systematic review supports this view.…”

Flowtron foot-pumps for prevention of venous thromboembolism in total hip and knee replacement

“…5 However untoward side effects including haemorrhagic complications and heparin induced thrombocytopenia (HIT) syndrome are frequent. 2,3,8,12,14,17 The controversy between the Orthopaedic surgeons and Cardiopulmonary physicians is still ongoing. 1,5 Therefore, we adopted an individualised strategy with mechanical prophylaxis as main tool against DVT and PE.…”