Prophylaxis Pre-Operative Single Dose Antibiotic Versus Conventional Antibiotic Therapy in Lichtenstein Tension Free Mesh Repair

Abstract

How to cite this article: K. Saravanan, A. Muthukumar. Prophylaxis pre-operative single dose antibiotic versus conventional antibiotic therapy in lichtenstein tension free mesh repair. International Journal of Contemporary Medicine Surgery and Radiology. 2019;4(2):B170-B172. MATERIAL AND METHODS This prospective comparative study was conducted department of General Surgery, Government Theni Medical College Hospital in elective Lichtenstein tension-free mesh A B S T R A C T Introduction: Surgical antibiotic prophylaxis (SAP) refers to the utilization of antibiotics for the prevention of surgical site infections (SSIs). SSIs impact on both the patient and health care system through increased mortality and morbidity, prolonged hospital admission, reduced the quality of life and additional financial costs for ongoing inpatient and outpatient treatment. Aim: To study the effect of single-dose antibiotic prophylaxis given 30 minutes prior to surgery with conventional antibiotic therapy. Material and Methods: Total of 50 patients were randomized to 25 each group. All patients in the study group undergoing surgery were given 400 mg parenteral ciprofloxacin 30 min prior to surgery. In the control group, the patients were given 2 days parenteral ciprofloxacin 400 mg twice a day and the next 5 days the same antibiotics were given in oral route, after surgery. The outcome in terms of duration of surgery, surgical site infection, cost and antibiotic side effects were then compared. Results: Out of 50 patients, the incidence of postoperative infection 10% (5 patients), 3 cases in the control group and 2 patients prophylactic antibiotic group. No change in the management protocol was done. None developed antibiotic side effects in the study group. Control group patients developed study effects of nausea, vomiting and diarrhoea. Conclusion: Prophylactic single-dose antibiotic is effective in preventing surgical site infection and is cost-effective in patients undergoing Lichtenstein tension-free mesh repair.