Propofol should be the agent of choice for caesarean section under general anaesthesia

General anesthesia for caesarean section

“…Propofol, in a dose sufficient for induction and to prevent maternal awareness (2.5 mg/kg), depresses the infant more than thiopental and causes a reduction in maternal blood pressure [17][18][19]. The latter effect can be advantageous in the hypertensive patient as compared with thiopental, propofol reduces the cardiovascular response to laryngoscopy and tracheal intubation [20].…”

Infective endocarditis complicated by rupture of intracranial mycotic aneurysm during pregnancy

“…18 However, propofol is highly lipid soluble and placental transfer occurs rapidly; this may be associated with low neurobehavioral scores in the baby. 19 Remifentanil, with its rapid onset and short context-sensitive half-time, is a popular opioid among neuroanaesthetists. It is not commonly used in obstetrics.…”

General anesthesia for cesarean section: are we doing it well?

“…The recommended dose of propofol is approximately 2.0–2.8 mg/kg. However, propofol 2.5 mg/kg is a sufficient dose for induction to prevent maternal awareness; it causes worse baby outcomes and higher reduction in maternal blood pressure than thiopental does [ 27 , 28 ]. Furthermore, propofol 2 mg/kg compared with thiopental 4 mg/kg tends to have a higher incidence of Apgar scores of 7 or less [ 29 ].…”