Propofol versus isoflurane for endoscopic sinus surgery

Pavlin, J.; Colley, Peter S.; Weymuller, Ernest A.; Norman, Gail Van; Gunn, Holly C.; Koerschgen, Meagan E.

doi:10.1016/s0196-0709(99)90018-2

Cited by 116 publications

(117 citation statements)

References 7 publications

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“…Despite the lower perfusion pressure, tissue perfusion is increased following vasodilatation. Isofl urane may increase the velocity of blood fl ow in the muscles two or even three times (2). Therefore, isofl urane usage during FESS may increase perfusion of the nasal mucous membrane and surgical bleeding as well.…”

Section: Choice Of Anesthetic Agentmentioning

confidence: 99%

“…The ethmoid, sphenoid, and frontal sinuses are supplied with blood by the branches of a. carotis interna: the ethmoidal artery and the supraorbital artery. Propofol is known to reduce cerebral circulation and metabolism (2). Therefore, by reducing cerebral circulation and ar-terial blood infl ow with propofol, circulation in the ethmoid, sphenoid, and frontal sinuses will be suppressed and working conditions in the surgical fi eld will be improved.…”

Section: Choice Of Anesthetic Agentmentioning

confidence: 99%

“…General anesthesia has the following apparent advantages: an immobile surgical fi eld for performing a surgical operation; effective protection of the respiratory tract; adequate analgesia and ventilation. The only serious limitation during general anesthesia is that bleeding is more intensive than during local anesthesia (1,2). Surgical bleeding decreases visibility of the surgical fi eld during an intervention and appears to be one of the most serious problems of FESS (2)(3)(4).…”

Section: Introductionmentioning

confidence: 99%

“…The only serious limitation during general anesthesia is that bleeding is more intensive than during local anesthesia (1,2). Surgical bleeding decreases visibility of the surgical fi eld during an intervention and appears to be one of the most serious problems of FESS (2)(3)(4). Reduced visibility of the surgical fi eld is related to an increased risk of dangerous vascular, orbital, and intracranial complications, prolonged duration of intervention, and reduced quality of intervention (1,5,6).…”

Section: Introductionmentioning

confidence: 99%

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A role of anesthesiologist in reducing surgical bleeding in endoscopic sinus surgery

et al. 2010

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Section: Choice Of Anesthetic Agentmentioning

confidence: 99%

Section: Choice Of Anesthetic Agentmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A role of anesthesiologist in reducing surgical bleeding in endoscopic sinus surgery

et al. 2010

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“…These may affect the duration and technical accuracy of procedures, which are of high importance in spinal surgeries, considering the proximity of operation field to neurological structures (1). Different methods have been used to minimize the operation field hemorrhage, including the use of local vasoconstrictors or inducing deliberate hypotension by means of antihypertensive agents, vasodilators, or the anesthetic drugs (1,2).…”

Section: Introductionmentioning

confidence: 99%

Ankle Sprains at a Military Male School: Taping Versus Bracing

Najafipour

Ahmadi

2014

J Arch Mil Med

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Background: Surgical treatment of lumbar intervertebral disc herniation is a critical procedure due to the proximity of the operation field to neural structures. Providing a bloodless field and optimizing surgeon vision is of high value in this regard. Total intravenous anesthesia with propofol and inhalation anesthesia with isoflurane are both used in spine surgeries. Both of these agents have vasodilator properties that could be benefited in inducing controlled hypotension as a blood sparing technique. We sought to compare propofol and isoflurane anesthesia in terms of intraoperative bleeding and hemodynamic changes. Methods: After obtaining ethics approval and informed consent, 88 Iranian patients with American society of anesthesiology score 1 and 2 were randomly divided into two groups. The ISO group received isoflurane and the PRO group received propofol as the main anesthetic agent. Hemodynamic changes, intraoperative bleeding, urinary output, and surgeon satisfaction score were recorded. Results: The two groups were similar in demographic characteristics (for age P = 0.072; for gender P = 0.286). The ISO group had significantly lower blood pressure after 30 minutes of anesthesia (P = 0.01). Intraoperative bleeding in terms of qualitative and quantitative measures was lower in the ISO group (P = 0.001). Isoflurane anesthesia was also associated with a higher surgeon satisfaction score (P = 0.01). Conclusions: Our findings showed that isoflurane as a volatile agent provides a bloodless field better than does propofol through TIVA.

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