Propolis extracts exhibit an immunoregulatory activity in an OVA-sensitized airway inflammatory animal model

Anti-inflammatory activity of quercetin and isoquercitrin in experimental murine allergic asthma

“…Therefore, it would be desirable to create a compound that acts like a steroid but has fewer side effects [37]. The potential of natural products to inhibit eosinophilic infl ammation was recently demonstrated, both in experimental animal models [38,39] and in humans [40]. Many fl avonoids have been found to exert potent anti-allergic and anti-infl ammatory effects.…”

Suppression of interleukin 17 production by Brazilian propolis in mice with collagen-induced arthritis

“…The composition of propolis depends on variations in its geographical and botanical origin (Marcucci et al 2000). Propolis has been reported to have several biological effects including an immunomodulatory action (Orsatti et al 2010;Park et al 2004), anti-inflammatory (Borrelli et al 2002;Hu et al 2005;Jung et al 2008;Sy et al 2006), antioxidant (Korkina 2007), antiviral (Burdock 1998), antibacterial properties (Boukraa and Sulaiman 2009), and the ability to inhibit cell division (Aso et al 2004;Ishihara et al 2009;Najafi et al 2007). We wondered whether propolis has any effects on IL-17 production in vitro and in vivo.…”

Effects of propolis from different areas on mast cell degranulation and identification of the effective components in propolis

“…Effects of propolis extracts on the immune system have been reported, e.g., immunoregulation in an OVA-sensitized airway inflammatory animal model [6] and various immune cells including mast cells [7][8][9]. CAPE, one of the Chinese propolis components, has been reported to significantly inhibit asthmatic reactions in a mouse model [10].…”