Proposed Two-molecule Intercalation between Neighboring Base Pairs of DNA

Metal complexes of modified cyclen as catalysts for hydrolytic restriction of plasmid DNA

“…These results indicate clearly that the acridine group in these compounds interacts strongly with the double-stranded DNA, mostly through intercalation. Interactions of this nature between acridine derivatives and DNA have been previously observed in other related studies [23,36,37].…”