Propoxyphene (Darvon) Poisoning

Darvon® and the EEG

“…Its analgesic effects have been compared to codeine (Gruber et al 1956;Gruber 1957;Cass and Frederik 1963;Marrs et al 1959;Sadove et al 1961). Propoxyphene in overdosage is known to have central nervous system effects as manifested by stupor, coma, respiratory depression and convulsions (Cann and Verhulst 1960;Hyatt 1962;Frasier et al 1963;Storts 1963;Swarts 1964;Cawood and Thirkettle 1966;Karliner 1967). The purpose of this study was to evaluate the effects of Darvon on the EEG of normal subjects.…”