Prosexual Effect ofChrysactinia mexicanaA. Gray (Asteraceae), False Damiana, in a Model of Male Sexual Behavior

Abstract

Chrysactinia mexicana A. Gray (Asteraceae) and Turnera diffusa Willd (Turneraceae) are employed in traditional medicine as aphrodisiacs; however, there is no scientific evidence supporting the prosexual properties of C. mexicana. The aim of this study was to determine whether an aqueous extract of C. mexicana (Cm) stimulates rat male sexual behavior in the sexual exhaustion paradigm. Sexually exhausted (SExh) male rats were treated with Cm (80, 160, and 320 mg/kg), an aqueous extract of T. diffusa (Td), or yohimbine. The sexual exhaustion state in the control group was characterized by a low percentage of males exhibiting mounts, intromissions, and ejaculations and no males demonstrating mating behavior after ejaculation. Cm (320 mg/kg), Td, or yohimbine significantly increased the proportion of SExh rats that ejaculated and resumed copulation after ejaculation. In males that exhibited reversal of sexual exhaustion, Cm (320 mg/kg) improved sexual performance by reducing the number of intromissions and shrinking ejaculation latency. The effects of treatments on sexual behavior were not related with alterations in general locomotion. In conclusion, the prosexual effects of Cm, as well as those of Td, are established at a central level, which supports the traditional use of C. mexicana for stimulating sexual activity.

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“…Revista Bio Ciencias 6(2), e670. Benson, 2008;FEUM, 2013), aunque el efecto más conocido es como tónico y estimulante, por lo que ha adquirido popularidad como afrodisíaco (Estrada-Reyes et al, 2016). Los principales componentes bioactivos de T. diffusa incluyen flavonoides, como gonzalitosina I, apigenina y glucósidos derivados, luteolina y glucósidos derivados, cianoglucósido tetrafilina B, arbutina, un glucósido fenólico y los alcaloides damianina y cafeína.…”

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“…Ciencias 6(2), e670. Benson, 2008;FEUM, 2013), aunque el efecto más conocido es como tónico y estimulante, por lo que ha adquirido popularidad como afrodisíaco (Estrada-Reyes et al, 2016). Los principales componentes bioactivos de T. diffusa incluyen flavonoides, como gonzalitosina I, apigenina y glucósidos derivados, luteolina y glucósidos derivados, cianoglucósido tetrafilina B, arbutina, un glucósido fenólico y los alcaloides damianina y cafeína.…”

“…for the treatment of various diseases, including urinary tract infections, diabetes mellitus, malaria, diarrhea and peptic ulcers (Chevallier, 1996;Benson, 2008;FEUM, 2013) although the best known effect is as tonic and stimulant that has become popular as an aphrodisiac (Estrada-Reyes et al, 2016). The main bioactive components of T. diffusa include flavonoids, such as gonzalitosin I, apigenin and derived glycosides, luteolin and derived glycosides, cyanoglucoside tetrafillin B, arbutin a phenolic glycoside and the alkaloids damianin and caffeine.…”

Therapeutic Effects of Turnera diffusa Extract Against Amitriptyline-Induced Toxic Hepatic Inflammation

“…Additionally, Turnera diffusa Willd (damiana) is discovered plentifully in parched and semiarid areas like Mexico, Bolivia, Brazil, Central America and South America and it is utilized in elective medication in view of its remedial and viable properties against numerous illnesses, just as it was utilized as a sexual energizer and diuretic and its entrance into numerous drug items (Alcaraz-Melendez et al, 2007;Estrada-Reyes et al, 2016;Tousson et al, 2020b).…”