Prospective comparison of computed tomography enterography and magnetic resonance enterography for assessment of disease activity and complications in ileocolonic Crohnʼs disease

Fiorino, Gionata; Bonifacio, Cristiana; Peyrin–Biroulet, Laurent; Minuti, Francesco; Repici, Alessandro; Spinelli, Antonino; Fries, Walter; Balzarini, Luca; Montorsi, Marco; Malesci, Alberto; Danese, Silvio

doi:10.1002/ibd.21533

Cited by 206 publications

(163 citation statements)

References 36 publications

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“…MRE is very precise in determining the location and extension of the inflammatory lesions (sensitivity 74%, specificity 91%) in CD (5), which is very close to the precision demonstrated by CT enterography (18) and greater than the precision of ultrasound for locations in the jejunum and proximal ileum (19). In our series, the majority of the patients in whom an extension study was performed using MRE, disease activity was found in the jejunum and proximal ileum which led to a change in the therapeutic management of these patients due to having extensive disease.…”

Section: Discussionsupporting

confidence: 55%

Using of magnetic resonance enterography in the management of Crohn's disease of the small intestine: First year of experience

Mendoza

González-Lama

Taxonera

et al. 2012

Rev. esp. enferm. dig.

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Objective: to describe the experience at two tertiary centres during the first year of use of magnetic resonance enterography (MRE) for the management of Crohn's disease (CD): indications and influence of the technique in clinical decision making.Materials and methods: retrospective descriptive study in which patients who underwent MRE were included consecutively. Epidemiological and clinical data were collected from the patients, as well as the indication for the study and how it influenced clinical decision making in the 10 days following the radiological study.Results: 24 MREs were performed in suspected CD and 126 known CD; partial bowel obstruction in 53 patients (42%), monitoring of medical treatment in 34 (27%), due to incomplete ileocolonoscopy in 16 (13%), extension study of the small intestine in 15 (12%) and suspected complicated CD in 8 patients (6%). The MRE influenced in a change in treatment in 83 (55.3%) patients: 16 (10.7%) started with immunosuppressants, 41 (27.3%) with antiTNFa were started on or switched, 15 (10%) were ordered surgery and in 3 (2%) changed from combined therapy to monotherapy. The MRE had less influence on clinical decision making in the group in which the indication was suspected CD (p < 0.05).Conclusions: the use of MRE helped on decision making in more than half of patients, especially with regards to decisions related to the use of biological therapies and the indication for surgery. MRE was less useful in suspected CD patients

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Section: Discussionsupporting

confidence: 55%

Using of magnetic resonance enterography in the management of Crohn's disease of the small intestine: First year of experience

Mendoza

González-Lama

Taxonera

et al. 2012

Rev. esp. enferm. dig.

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“…US accuracy lower for disease proximal to terminal ileum US, CT, MRI all high accuracy for detection of fistulas, abscesses, stenosis. US higher false positive for abscesses Fiorino et al [43] , MRE significantly superior to CTE in detecting internal strictures: sensitivity (92% vs 85%), accuracy (95% vs 91%), specificity (90% vs 51%) Overall no significant difference in sensitivity and specificity of MRE and CTE in localising CD, bowel wall thickening, bowel wall enhancement, enteroenteric fistulas, detection of abdominal nodes, perivisceral fat enhancement Per segment analysis, MRE significantly superior to CTE in detecting ileal wall enhancement, with higher sensitivity (93% vs 81%) and accuracy (88% vs 81%), but lower specificity (72% vs 81%). MRE significantly superior in localising rectal disease, with higher accuracy (93% vs 85%), specificity (100% vs 50,9%) but lower sensitivity (72% vs 81%)…”

Section: Conventional Ct Mrementioning

confidence: 99%

“…MRE provides superior soft tissue contrast resolution compared to CTE, allowing detailed visualisation of inflammatory and fibrotic bowel wall [42] . A 2011 Italian prospective study by fiorino et al [43] compared MRE and CTE in 44 patients with ileocolonic CD. They found comparable accuracy between MRE and CTE in localising CD, assessing bowel wall thickening, bowel wall enhancement and enteroenteric fistula.…”

Section: Mrementioning

confidence: 99%

Diagnostic imaging and radiation exposure in inflammatory bowel disease

Zakeri¹,

Pollok²

2016

WJG

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“…Pesquisas recentes demonstraram uma precisão comparável entre RNM e TC na avaliação do espessamento da parede intestinal, aumento da parede e fístula enteroentérica. Contudo, a RNM foi superior a TC na detecção de estenoses e aumento da parede ileal (FIORINO et al, 2011).…”

Section: Ressonância Nuclear Magnéticaunclassified

Doença De Crohn

Papacosta¹,

Nunes²,

Pacheco³

et al. 2017

Rev Pat Tocantins

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INTRODUÇÃO: A doença de Crohn é qualificada como uma doença inflamatória intestinal, de caráter crônico, recidivante, transmural e que pode afetar qualquer parte do trato digestivo, desde a boca até o ânus, mas, principalmente, o intestino delgado e o cólon. São de cunho multifatorial, com prevalência e incidência variando de acordo com a genética, meio ambiente, microbiota intestinal e até mesmo um possível agente entérico infeccioso. É uma doença que afeta pessoas de várias idades, sexos e raças, apesar de se verificar maior incidência em jovens do sexo feminino e em regiões urbanas. METODOLOGIA: Trata-se de um artigo de revisão no qual, a partir das palavras “doença de Crohn” e “doença inflamatórias intestinais”, foi realizado busca por periódicos nos bancos de dados: PubMed, Scielo, Portal Periódicos CAPES e Google acadêmico. CONCLUSÃO: A doença de Crohn apresenta uma importante taxa de morbimortalidade no mundo, principalmente em regiões em franca urbanização e industrialização. O diagnóstico é um procedimento extremamente complicado devido a sua clínica inespecífica e pelos vários aspetos em comum com outras patologias. Dessa forma, ainda se faz necessário uma melhor investigação científica na área, com intuito de se desenvolver melhores técnicas diagnosticas e condutas a serem tomadas no seguimento e cura dessa patologia.Palavras-chave: Doença de Crohn, Doença inflamatórias intestinais, Diarreia. ABSTRACT INTRODUCTION: Crohn's disease is described as an inflammatory, chronic, recurrent, transmural inflammatory disease that can affect any part of the digestive tract, from the mouth to the anus, but especially the small intestine and colon. They are multifactorial, with prevalence and incidence varying according to genetics, environment, intestinal microbiota and even a possible infectious enteric agent. It is a disease that affects people of various ages, sexes and races, although there is a greater incidence in young women and in urban areas. METHODOLOGY: This is a review article in which, from the words "Crohn's disease" and "inflammatory bowel disease", a search was made for journals in the databases: PubMed, Scielo, Portal Periódicos CAPES and Google academic. CONCLUSION: Crohn's disease presents an important morbidity and mortality rate in the world, especially in regions where there is rapid urbanization and industrialization. Diagnosis is an extremely complicated procedure due to its nonspecific clinical and various aspects in common with other pathologies. Thus, a better scientific investigation in the area is still necessary, in order to develop better diagnostic techniques and behaviors to be taken in the follow-up and cure of this pathology. Keywords: Crohn's disease, Inflammatory bowel disease, Diarrhea.

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Prospective comparison of computed tomography enterography and magnetic resonance enterography for assessment of disease activity and complications in ileocolonic Crohnʼs disease

Abstract: MR and CT are equally accurate to assess disease activity and bowel damage in CD. MR may be superior to CT in detecting intestinal strictures and ileal wall enhancement. MR may represent an alternative technique to CT in assessing ileocolonic CD.

Cited by 206 publications

References 36 publications

Using of magnetic resonance enterography in the management of Crohn's disease of the small intestine: First year of experience

Using of magnetic resonance enterography in the management of Crohn's disease of the small intestine: First year of experience

Diagnostic imaging and radiation exposure in inflammatory bowel disease

Doença De Crohn

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