Prospective Epidemiological Research Studies in Iran (the PERSIAN Cohort Study): Rationale, Objectives, and Design

Poustchi, Hossein; Eghtesad, Sareh; Kamangar, Farin; Etemadi, Arash; Keshtkar, Abbasali; Hekmatdoost, Azita; Mohammadi, Zahra; Mahmoudi, Zohreh; Shayanrad, Amaneh; Roozafzai, Farzin; Sheikh, Mahdi; Jalaeikhoo, Alireza; Somi, Mohammad Hossein; Mansour-Ghanaei, Fariborz; Najafi, Farid; Bahramali, Ehsan; Mehrparvar, Amirhoushang; Ansari‐Moghaddam, Alireza; Enayati, Ahmadali; Nadimi, Ali Esmaeili; Rezaianzadeh, Abbas; Saki, Nader; Alipour, Fateme; Kelishadi, Roya; Rahimi-Movaghar, Afarin; Aminisani, Nayyereh; Boffetta, Paolo; Malekzadeh, Reza

doi:10.1093/aje/kwx314

Cited by 518 publications

(585 citation statements)

References 15 publications

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“…The cohort population for each province has been presented in Appendix 1. Other detailed information on the cohort method can be found in the past studies [27,28].…”

Section: Data Source and Variablesmentioning

confidence: 99%

Socioeconomic - related inequalities in overweight and obesity: findings from the PERSIAN cohort study

et al. 2020

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Background: Overweight and obesity are major health concerns worldwide, with adverse health consequences during the life span. This study measured socioeconomic inequality in overweight and obesity among Iranian adults. Methods: Data were extracted from 129,257 Iranian adults (aged 35 years and older) participated in the Prospective Epidemiologic Research Studies in IrAN (PERSIAN) in 14 provinces of Iran in 2014. Socioeconomic-related inequality in overweight and obesity was estimated using the Concentration Index (C n ). The C n further decomposed to find factors explaining the variability within the Socioeconomic related inequality in overweight and obesity. Results: Of the total number of participants, 1.98, 26.82, 40.76 and 30.43% had underweight, normal weight, overweight and obesity respectively. The age-and sex standardized prevalence of obesity was higher in females than males (39.85% vs 18.79%). People with high socioeconomic status (SES) had a 39 and 15% higher chance of being overweight and obese than low SES people, respectively. The positive value of C n suggested a higher concentration of overweight (0.081, 95% confidence interval [CI]; 0.074-0.087) and obesity (0.027, 95% CI; 0.021-0.034) among groups with high SES. There was a wide variation in socioeconomic-related inequality in overweight and obesity rate across 14 provinces. The decomposition results suggested that SES factor itself explained 66.77 and 89.07% of the observed socioeconomic inequalities in overweight and obesity among Iranian adults respectively. Following SES, province of residence, physical activity, using hookah and smoking were the major contributors to the concentration of overweight and obesity among the rich. Conclusions: Overall, we found that overweight and obesity is concentrated among high SES people in the study population. . Accordingly, it seems that intersectional actions should be taken to control and prevent overweight and obesity among higher socioeconomic groups.

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“…The cohort population for each province has been presented in Appendix 1. Other detailed information on the cohort method can be found in the past studies [27,28].…”

Section: Data Source and Variablesmentioning

confidence: 99%

Socioeconomic - related inequalities in overweight and obesity: findings from the PERSIAN cohort study

et al. 2020

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“…In the study, we utilized a subset of data which was collected for Tabari cohort study (TCS). TCS is part of the national cohort, Prospective Epidemiological Research Studies in Iran (PERSIAN) [13,14]. The objective and details of TCS have been explained elsewhere [15].…”

Section: Methodsmentioning

confidence: 99%

“…Data collection method includes structural questionnaire and obtaining blood, urine, hair, and nail samples. The questionnaire used in the study was a standardized questionnaire in which details and features are described in cohort profiles [13,14]. Items of questionnaire consist of general information, socioeconomic status, occupational history, type of fuel used, characteristics of the habitat, life style, history of fertility, history of chronic diseases, drug use, familial history of diseases, oral health, physical examination, physical disabilities, sleep status, physical activity, personal habits (smoking and drinking), food frequency, food supplements, water drink, dietary habits, and exposure to pesticides.…”

Section: Methodsmentioning

confidence: 99%

Age of Natural Menopause and Related Factors among the Tabari Cohort

et al. 2020

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Objectives:The age of menopause is affected by several factors. In this study we aimed to identify the age of natural menopause and its related factors in a large-scale population-based cohort in Iran. Methods: In this study, a subset of data collected during the enrollment phase of the Tabari cohort Study was utilized. Reproductive history and other related data were collected using a structured questionnaire. Blood samples were obtained from all participants. Data were analyzed using chi-square test, independent t test, and ANOVA as well as a multivariate linear regression model. Results: Among participants of the Tabari cohort, 2,753 were menopausal women. The mean age of natural and induced menopause was 49.2 ± 4.7 and 43.2 ± 6.4 years, respectively (P = 0.001). The number of pregnancies, duration of breastfeeding, level of education, residency, presence of thyroid disease, and body mass index affected the age of menopause. After adjustments for confounding variables, the number of pregnancies remained significantly associated with late menopause. Conclusions: The age of natural menopause in this study was similar to that in other studies, and the number of pregnancies was positively associated with the age of menopause after adjustments for confounding variables.

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“…14 One of the major categories of Azar cohort’s questionnaire was about using tobacco and drugs. Other variables in this questionnaire include sex, age, occupation, marital status, education level, disease and medicine use, physical activity, etc.…”

Section: Methodsmentioning

confidence: 99%

“…This study aimed at examining the prevalence and validity of self-reported drug use in the pilot phase of Azar cohort study; a province-level of the Prospective Epidemiological Research Studies of the Iranian adults (PERSIAN) which is a nationwide cohort study launched in 2014. 14 …”

Section: Introductionmentioning

confidence: 99%

The validity of self-reported drug use with urine test: results from the pilot phase of Azar cohort study

Ashrafi

Aminisani

Soltani

et al. 2018

Health Promot Perspect

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Background: The present study aimed at assessing the validity of self-reported drug use in people aged 35 and older in a pilot phase of a population-based cohort study. Methods: A total of 1038 adults over 35 years old in Khamene city in East Azerbaijan province were recruited for the pilot phase of Azar cohort; a province-level of a nationwide PERSIAN cohort study completing a questionnaire and providing biological samples from October to December 2014. Information about the history and duration of smoking tobacco, using drug and medication were obtained by the physician. The validity of the drug use was assessed through comparing the questionnaire response with three urine strip tests for the detection of morphine, amphetamine and methamphetamine among 259 randomly selected subjects. Results: The prevalence of drug use according to self-report was 2.6% (95% CI: 1.7%-3.8%).One-step drug test as the gold standard for the use of drug self-reported demonstrated a sensitivity(95% CI) and specificity 15% (10-22) and 99.7% (98.9%-99.9%) respectively. All participants with positive self-report were male; however, in the urine analysis drug test, it was positive for 7out of 68 randomly selected women. Conclusion: The validity of self-reported drug use in this population was low; therefore, the self reported use of the drug should be used with caution in this population. It is recommended to use alternative techniques to improve the validity of data using the self-report procedure.

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Prospective Epidemiological Research Studies in Iran (the PERSIAN Cohort Study): Rationale, Objectives, and Design

Cited by 518 publications

References 15 publications

Socioeconomic - related inequalities in overweight and obesity: findings from the PERSIAN cohort study

Socioeconomic - related inequalities in overweight and obesity: findings from the PERSIAN cohort study

Age of Natural Menopause and Related Factors among the Tabari Cohort

The validity of self-reported drug use with urine test: results from the pilot phase of Azar cohort study

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