is undoubtedly one of the most famous scientists and psychiatrists in the field of attentiondeficit/hyperactivity disorder (ADHD) worldwide. In 2018, he celebrated his 65th birthday, which led colleagues and friends to dedicate this special edition to him. Jan's broad expertise, ranging from clinical work in children, adolescents, and adults with ADHD to multiple aspects of etiological and treatment research of the disorder, is reflected in this issue. It contains papers on ADHD diagnosis and treatment, comorbidity and cognition, neuroimaging and genetics. Jan Buitelaar studied medicine and philosophy at the University of Utrecht in The Netherlands, where he subsequently also obtained his Ph.D. In 1995, only 4 years after his doctorate, he was appointed professor of Biopsychosocial Determinants of Human Behaviour in Utrecht. Seven years later, in 2002, he moved to the Radboud University Medical Center in Nijmegen, where he took over the