Prospective multicenter evaluation of colon capsule examination indicated by colonoscopy failure or anesthesia contraindication

Abstract

This study shows the feasibility and the usefulness of CCE in the situation of colonoscopy failure or contraindication. The colon capsule modality should be tested against other available approaches, such as virtual colonoscopy or repeat colonoscopy by an expert.

Therapeutic impact of colon capsule endoscopy with PillCam™ COLON 2 after incomplete standard colonoscopy: a Spanish multicenter study

“…These cases represented almost half of the patients with new findings in CCE-2. These results are in concordance with other previously reported (13,18,19). However, CCE-2 did not visualize new lesions in segments previously visualized using colonoscopy.…”

Colon capsule versus CT colonography in patients with incomplete colonoscopy: a prospective, comparative trial

“…All these results support CTC as the imaging modality of choice in case of incomplete colonoscopy since it allows the evaluation of the non-visualised part of the colon and increases the diagnostic yield of masses and larger polypoid lesions 19 32. Previous studies, all performed using the first generation of colon capsule, also evaluated the role of CCE or CTC in patients with an incomplete colonoscopy 26 27 33. Pioche et al 33 for the first time, in a prospective multicenter series of 107 patients (ie, 77 with a colonoscopy failure and 30 with a colonoscopy contraindication), reported a 93% capsule completion rate and a 33.6% CCE diagnostic yield.…”

Frequency and efficacy of additional investigations following incomplete colonoscopies: A population-based analysis

“…Variable stiffness, small-calibre and simple-balloon colonoscopies might be useful in patients with definite failure after repeat colonoscopy [31][32][33]. Colon capsule endoscopy might be an alternative procedure for patients with non-occlusive incomplete colonoscopy [34][35][36].…”