Prospective Risk Factors for Increased Central Augmentation Index in Men and Women

Kumar, Prithvi Shiva; Medina‐Lezama, Josefina; Morey-Vargas, Oscar L.; Zamani, Payman; Bolaños-Salazar, Juan F.; Chirinos, Diana A.; Haines, Philip; Khan, Zubair; Coacalla-Guerra, Johanna C.; Davalos-Robles, Maria E.; Llerena-Dongo, Gladys R.; Zapata-Ponze, Mardelangel; Chirinos, Julio A.

doi:10.1093/ajh/hpu093

Cited by 11 publications

(3 citation statements)

References 35 publications

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“…Moreover, the study of the parameters derived from the forward pulse wave, generated by the cardiac systole, and those derived from the retrograde pulse wave, generated in the arterial branch points, provides information about the vascular tree [17]. Such parameters include the central augmentation index (CAIx)-which is the most used substitute to analyse the reflection of the arterial wave-, the peripheral augmentation index (PAIx), augmentation pressure (AP), ejection duration (ED) and subendocardial viability ratio (SEVR) [18]. These central hemodynamic parameters show greater association with morbimortality by cardiovascular diseases [19] than peripheral arterial pressure, and they present a different response of antihypertensive drugs [20,21].…”

Section: Introductionmentioning

confidence: 99%

Long-Term Effectiveness of a Smartphone App and a Smart Band on Arterial Stiffness and Central Hemodynamic Parameters in a Population with Overweight and Obesity (Evident 3 Study): Randomised Controlled Trial

Gómez‐Sánchez

Lugones-Sánchez

et al. 2022

Nutrients

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Background: mHealth technologies could help to improve cardiovascular health; however, their effect on arterial stiffness and hemodynamic parameters has not been explored to date. Objective: To evaluate the effect of a mHealth intervention, at 3 and 12 months, on arterial stiffness and central hemodynamic parameters in a sedentary population with overweight and obesity. Methods: Randomised controlled clinical trial (Evident 3 study). 253 subjects were included: 127 in the intervention group (IG) and 126 in the control group (CG). The IG subjects were briefed on the use of the Evident 3 app and a smart band (Mi Band 2, Xiaomi) for 3 months to promote healthy lifestyles. All measurements were recorded in the baseline visit and at 3 and 12 months. The carotid-femoral pulse wave velocity (cfPWV) and the central hemodynamic parameters were measured using a SphigmoCor System® device, whereas the brachial-ankle pulse wave velocity (baPWV) and the Cardio Ankle Vascular Index (CAVI) were measured using a VaSera VS-2000® device. Results: Of the 253 subjects who attended the initial visit, 237 (93.7%) completed the visit at 3 months of the intervention, and 217 (85.3%) completed the visit at 12 months of the intervention. At 12 months, IG showed a decrease in peripheral augmentation index (PAIx) (−3.60; 95% CI −7.22 to −0.00) and ejection duration (ED) (−0.82; 95% CI −1.36 to −0.27), and an increase in subendocardial viability ratio (SEVR) (5.31; 95% CI 1.18 to 9.44). In CG, cfPWV decreased at 3 months (−0.28 m/s; 95% CI −0.54 to −0.02) and at 12 months (−0.30 m/s, 95% CI −0.54 to −0.05), central diastolic pressure (cDBP) decreased at 12 months (−1.64 mm/Hg; 95% CI −3.19 to −0.10). When comparing the groups we found no differences between any variables analyzed. Conclusions: In sedentary adults with overweight or obesity, the multicomponent intervention (Smartphone app and an activity-tracking band) for 3 months did not modify arterial stiffness or the central hemodynamic parameters, with respect to the control group. However, at 12 months, CG presented a decrease of cfPWV and cDBP, whereas IG showed a decrease of PAIx and ED and an increase of SEVR.

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Section: Introductionmentioning

confidence: 99%

Long-Term Effectiveness of a Smartphone App and a Smart Band on Arterial Stiffness and Central Hemodynamic Parameters in a Population with Overweight and Obesity (Evident 3 Study): Randomised Controlled Trial

Gómez‐Sánchez

Lugones-Sánchez

et al. 2022

Nutrients

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“…10 –13 Additionally, in our patient group with psoriasis, we measured the central augmentation index (cAIx), which is derived from the arterial wave reflection demonstrating central aortic pressure. 14…”

Section: Introductionmentioning

confidence: 99%

Assessment of Arterial Stiffness in Korean Patients With Psoriasis by Cardio-Ankle Vascular Index

et al. 2016

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Many recent studies have suggested that psoriasis, a chronic, inflammatory, immune-mediated skin disease, is associated with increased risk of cardiovascular disease (CVD). We aimed to compare arterial stiffness in psoriasis and control patient groups using the cardio-ankle vascular index (CAVI) and to determine whether psoriasis is an independent risk factor for CVD. A total 103 patients with psoriasis and 103 age- and sex-matched controls were enrolled. Compared with controls, the patients showed a higher CAVI ( P = .03), particularly patients older than 40 years. The duration of psoriasis exhibited a positive correlative tendency with CAVI ( P = .066). Moreover, psoriasis is an independent predictor of arterial stiffness after adjusting for other factors ( P = .011). We suggest that psoriasis can be a risk factor for CVD, and older patients with psoriasis of longer disease duration should be monitored carefully for cardiovascular risk.

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“…Figura 1: Gráfico comparativo de envejecimiento vascular normal vs. acelerado 13 El Síndrome de EVA se caracteriza por la presencia asociada de 14,15 :…”

Section: Envejecimientounclassified

Impacto de la obesidad y de otros factores de riesgo cardiovascular sobre los niveles circulantes de mediadores de inflamación

Cuadra San Miguel

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Prospective Risk Factors for Increased Central Augmentation Index in Men and Women

Cited by 11 publications

References 35 publications

Long-Term Effectiveness of a Smartphone App and a Smart Band on Arterial Stiffness and Central Hemodynamic Parameters in a Population with Overweight and Obesity (Evident 3 Study): Randomised Controlled Trial

Long-Term Effectiveness of a Smartphone App and a Smart Band on Arterial Stiffness and Central Hemodynamic Parameters in a Population with Overweight and Obesity (Evident 3 Study): Randomised Controlled Trial

Assessment of Arterial Stiffness in Korean Patients With Psoriasis by Cardio-Ankle Vascular Index

Impacto de la obesidad y de otros factores de riesgo cardiovascular sobre los niveles circulantes de mediadores de inflamación

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