The research concerns the efficient development of low-potential thermal waters in the East-Ciscaucasian artesian basin. A technology is proposed for the integrated development of low-temperature thermal water, using its heat potential for district heating and hot water supply, as well the water itself for various water management purposes, with its quality previously brought to the standards of drinking water. Various chemical water treatment units are suggested for this purpose, with their design and technological features being formed depending on the quality of the source water. The system will enable the maximization of the resource potential of the geothermal well and its all-year-round operation. The paper shows the efficiency of using the potential of geothermal energy resources in energy- biological complexes. The geothermal-biogas technology with the integrated application of thermal waters for various needs is presented. Such thermal water utilization provides for the most efficient use of its thermal potential with a decrease in temperature to a value close to the ambient temperature.