Prospects of using bioactive compounds in nanomaterials surface decoration and their biomedical purposes

Abbas, Heba S.; Mahmoud, Amr M.; Wahed, Rania A.; Elsantawy, Menna Allah A.; Hamdy, Naglaa M.; Ismail, Salma E. S.; Nabil, Manal A.

doi:10.1007/s40089-021-00355-9

Cited by 9 publications

(4 citation statements)

References 110 publications

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“…During the last decade, fucoidan has been widely studied due to its high biological activity. The search for new drugs has generated interest in fucoidans from microalgae [ 201 ]. During the last decade, fucoidans isolated from different types of microalgae have been widely studied regarding their anticoagulant and antithrombotic, antiviral, antitumor and immunomodulatory, anti-inflammatory, blood-lipid-lowering, antioxidant and anti-complementary properties, activity against hepatopathy, uropathy, protective effects for gastric pathology, and therapeutic potential in surgery.…”

Section: Macroalgaementioning

confidence: 99%

Algae: Study of Edible and Biologically Active Fractions, Their Properties and Applications

Babich

Сухих

Larina

et al. 2022

Plants

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The beneficial properties of algae make them perfect functional ingredients for food products. Algae have a high energy value and are a source of biologically active substances, proteins, fats, carbohydrates, vitamins, and macro- and microelements. They are also rich in polyunsaturated fatty acids, proteins, mycosporine-like amino acids, polysaccharides, polyphenols, carotenoids, sterols, steroids, lectins, halogenated compounds, polyketides, alkaloids, and carrageenans. Different extraction parameters are used depending on the purpose and the substances to be isolated. In this study, the following parameters were used: hydromodule 1:10 and an extraction duration of 1–2 h at the extraction temperature of 25–40 °C. A 30–50% solution of ethanol in water was used as an extractant. Algae extracts can be considered as potential natural sources of biologically active compounds with antimicrobial activity and antiviral properties. The content of crude protein, crude fat, and carbohydrates in U. Prolifera, C. racemosa var. peltata (Chlorophyta), S. oligocystum and S. fusiforme (SF-1) was studied. It was found that C. muelleri (Bacillariophyta), I. galbana (Haptophyta), and T. weissflogii (Bacillariophyta) contain about 1.9 times more omega-3 than omega-6 fatty acids. N. gaditana (Ochrophyta), D. salina (Chlorophyta), P. tricornutum (Bacillaryophyta) and I. galbana (Haptophyta) extracts showed inhibitory activity of varying intensities against E. coli or P. aeruginosa. In addition, algae and algae-derived compounds have been proposed to offer attractive possibilities in the food industry, especially in the meat sector, to evolve functional foods with myriad functionalities. Algae can increase the biological activity of food products, while the further study of the structure of compounds found in algae can broaden their future application possibilities.

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Section: Macroalgaementioning

confidence: 99%

Algae: Study of Edible and Biologically Active Fractions, Their Properties and Applications

Babich

Сухих

Larina

et al. 2022

Plants

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“…There is increasing interest in utilizing plant extracts as alternative and sustainable sources for synthesizing nanoparticles, particularly ZnO NPs. Plant extracts contain diverse bioactive compounds such as phenols, flavonoids, terpenoids, and alkaloids, capable of acting as both reducing and stabilizing agents in NPs synthesis [55]. This green approach is considered safer, environmentally friendly, and more sustainable compared to conventional methods involving harsh chemicals and high temperatures [56].…”

Section: Mechanism Of Formation Of Zno Npsmentioning

confidence: 99%

Biosynthesis and antibacterial activity of ZnO nanoparticles using Buchanania obovata fruit extract and the eutectic-based ionic liquid

Jabbar,

Barzinjy

2024

Nanotechnology

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The fruit extract of Buchanania Obovata and the eutectic-based ionic liquid were utilized, in an eco-friendly, inexpensive, simple method, for synthesizing zinc oxide nanoparticles (ZnO NPs). The influence of the reducing, capping and stabilizing agents, in both mediums, on the structure, optical, and morphological properties of ZnO NPs was extensively investigated. The surface plasmon resonance peaks were observed at 340 nm and 320 nm for the fruit-based and the eutectic-based ionic liquid mediums, respectively, indicating the formation of ZnO NPs. XRD results confirmed the wurtzite structure of the ZnO NPs, exhibiting hexagonal phases in the diffraction patterns. The SEM and TEM images display that the biosynthesized ZnO NPs exhibit crystalline and hexagonal shape, with an average size of 40 nm for the fruit-based and 25 nm for the eutectic-based ionic liquid. The BET surface area analysis, revealed a value ~13 m2 g−1 for ZnO NPs synthesized using the fruit extract and ~29 m2 g−1 for those synthesized using the eutectic-based ionic liquid. The antibacterial activity of the biosynthesized ZnO NPs was assessed against clinically isolated Gram-negative (E. coli) and Gram-positive (S. aureus) bacterial strains using the inhibition zone method. The ZnO NPs produced from the eutectic-based ionic liquids confirmed superior antibacterial activity against both S. aureus and E. coli compared to those mediated by the utilized fruit extract. At a concentration of 1000, the eutectic-based ionic liquid mediated ZnO NPs displayed a maximum inhibition zone of 16 mm against S. aureus, while against E. coli, a maximum inhibition zone of 15 mm was observed using the fruit extract mediated ZnO NPs. The results of this study showed that the biosynthesized ZnO NPs can be utilized as an efficient substitute to the frequently used chemical drugs and covering drug resistance matters resulted from continual usage of chemical drugs by users.

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“…In nano-biotechnology, living entities of both prokaryotic and eukaryotic origin include cyanobacteria, bacteria, viruses, algae, actinomycetes, fungi, yeasts, and plants. The ability of each biological system to provide metallic nanoparticles differs (Abbas et al, 2021 andArpagaus andSchafroth, 2009). However, because of their enzymatic activity and inherent metabolic activities, not all living species could create nanoparticles.…”

Section: Green Synthesesmentioning

confidence: 99%

“…Herbal medications continue to be the most common source of pharmaceuticals, and their side effects are far less severe than those of standard medicine, but they have considerable limitations. The most essential technique for addressing this issue is nanotechnology, which is an extremely talented technique for boosting the use of herbal medicine or, more particularly, re-discovering its potential as a pharmaceutical formulation (Abbas et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

Nanotechnology and Its Prospective Role in Using Bioactive Compounds to Fight Covid 19 Infection in This Era

Hamdy,

El Sayed,

Allm

et al. 2023

Egyptian Journal of Desert Research

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TIs or pneumonia, which account for 15% of all pediatric fatalities under the age of five and cause significant morbidity, continue to be a serious global health issue. The most dangerous infection lately COVID-19 associated with bacterial superinfections, which results in a fatal acute respiratory infection marked by shortness of breath. Scientists continue to face significant challenges in the development of vaccines and antiviral or antibacterial medications to treat these diseases. Recently, Bioactive natural products from a variety of plants and organisms, such as bacteria, fungi, and algae, hold promise as treatments for cancer, bacterial infections, inflammatory diseases, and other medical conditions. To facilitate the transport of these bioactive compounds to a particular target, nanoparticles drug delivery system can be adopted. Nanotechnology has been recognized as an essential tool in vast human medical fields. The goal of this review is to highlight prior and ongoing research on naturally occurring active nanomaterials as antiviral or antimicrobial agents, particularly for diseases of the modern era like COVID-19, and to R 514 Naglaa M. Hamdy et al.

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Prospects of using bioactive compounds in nanomaterials surface decoration and their biomedical purposes

Cited by 9 publications

References 110 publications

Algae: Study of Edible and Biologically Active Fractions, Their Properties and Applications

Algae: Study of Edible and Biologically Active Fractions, Their Properties and Applications

Biosynthesis and antibacterial activity of ZnO nanoparticles using Buchanania obovata fruit extract and the eutectic-based ionic liquid

Nanotechnology and Its Prospective Role in Using Bioactive Compounds to Fight Covid 19 Infection in This Era

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