2006
DOI: 10.1016/j.ijrobp.2005.08.016
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Prostate position variability and dose–volume histograms in radiotherapy for prostate cancer with full and empty bladder

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Cited by 94 publications
(53 citation statements)
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“…NIDDM, however, was included due to the impact previously shown [9,10]. The negative correlation between the bladder volume and the dosimetric factor PC1 is expected due to the inclusion of larger relative bladder volume in the high dose region in patients with smaller/empty bladder [30]. As posttreatment symptomology is more logically explained by the bladder dosimetry rather than the bladder size itself, only PC1 is included as a candidate.…”
Section: Variable Selection and Multivariate Analysismentioning
confidence: 99%
“…NIDDM, however, was included due to the impact previously shown [9,10]. The negative correlation between the bladder volume and the dosimetric factor PC1 is expected due to the inclusion of larger relative bladder volume in the high dose region in patients with smaller/empty bladder [30]. As posttreatment symptomology is more logically explained by the bladder dosimetry rather than the bladder size itself, only PC1 is included as a candidate.…”
Section: Variable Selection and Multivariate Analysismentioning
confidence: 99%
“…For men receiving dose-escalated radical prostate radiotherapy, a consistent bladder volume between planning and treatment is vital. Although there are differing opinions on the influence of bladder volume on interfraction prostate position [1][2][3][4][5][6][7], the influence of the irradiated bladder volume on acute and late urinary [8] and bowel toxicity [2,9] has been well documented.Despite the apparent importance of controlling bladder volume for prostate radiotherapy, there is surprisingly limited research into the provision of bladder-filling instructions that produce acceptable dose-volume histograms (DVHs) and provide a reproducible bladder volume from planning through to treatment [1-2, 10, 11] rather than an unreliable and misleading snapshot at the time of planning.This study was designed to first validate bladder volume measurements using a non-invasive transabdominal bladder ultrasound device (BVI 6400 Bladderscan, Verathon Medical UK, Sandford, UK) before using it to evaluate the effectiveness of standardised bladder-filling instructions in achieving a consistent and reproducible bladder volume from the time of planning and during each daily fraction of radical radiotherapy for prostate cancer. The data obtained would then be used to inform changes in bladder-filling instructions before future re-evaluation.…”
mentioning
confidence: 99%
“…For men receiving dose-escalated radical prostate radiotherapy, a consistent bladder volume between planning and treatment is vital. Although there are differing opinions on the influence of bladder volume on interfraction prostate position [1][2][3][4][5][6][7], the influence of the irradiated bladder volume on acute and late urinary [8] and bowel toxicity [2,9] has been well documented.…”
mentioning
confidence: 99%
“…dozimetrik çalışmalarında bağırsak dozunun; boş mesane ile tedaviye giren hastalarda olguların %37'sinde, dolu mesane ile girenlerde ise sadece %3'ünde tanımlanan dozun %90'ına ulaştığını gözlemişlerdir. [26] Yoğunluk ayarlı radyoterapi ve VMAT ile tü- mör çevresindeki dokularda hızlı doz düşüşü meydana gelmektedir. Bundan dolayı tedavi başarısı RT dozunun doğru yere verilebilmesine bağlıdır.…”
Section: Discussionunclassified