Prostatic carcinoma bilateral iris metastases

Šarenac, Tatjana; Janicijevic-Petrovic, Mirjana; Srećković, Sunčica; Radovanović, Milan; Vulović, Dejan; Janićijević, Katarina

doi:10.17305/bjbms.2012.2514

Cited by 9 publications

(3 citation statements)

References 13 publications

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“…5 Adenocarcinoma of the prostate is implicated in 3.6% to 4% of all orbital metastases; among them, metastases to the uvea have been commonly reported. [6][7][8] In very rare cases, metastases to the external rectus muscle and the optic nerve tract have been indicated. 9 When the disease metastasizes to the orbit, symptoms such as decreased vision, impaired eye movement, diplopia, and increased intraocular pressure are observed due to compression of the intraorbital tissue.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Prostate Carcinoma Metastasis in the Orbital Apex

et al. 2020

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Prostate cancer (PC) is prone to bone metastases, but very rarely it can spread to soft tissues. In the head and neck region, PC can metastasize to the orbital soft tissue, causing various symptoms such as vision loss. In this report, we describe the case of a 79-year-old man with PC metastasis in the orbital apex. He presented to an ophthalmologist at our hospital with progressively worsening vision in his left eye over 3 to 4 months. He complained of a drooping eyelid in the same eye; thus, intracranial disease was suspected. Closer inspection with head computed tomography revealed a space-occupying lesion from the orbit to the posterior ethmoid sinus, and he was referred to our department. He had a history of PC, and we performed endoscopic sinus surgery for the diagnosis of malignancy, including metastasis of PC. As a result, the mass was diagnosed as PC metastasis by pathological examination. The patient began androgen blockade therapy and 3 months postoperatively, magnetic resonance imaging revealed that the extraconal orbital mass had decreased significantly. It is important to determine the metastases of PC in the paranasal region when the patient has a preexisting medical history.

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Section: Discussionmentioning

confidence: 99%

A Rare Case of Prostate Carcinoma Metastasis in the Orbital Apex

et al. 2020

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“…However, soft tissue metastasis to the orbit is extremely rare. Most cases of soft tissue orbital metastasis secondary to PC involve the uveal tract [ 13 - 17 ] ( Table 1 ). PC is the most common primary cancer to metastasize to the iris (uveal tract) and the reported incidence ranges from 8% to 10% [ 18 , 19 ].…”

Section: Discussionmentioning

confidence: 99%

Extraconal Orbital Soft Tissue Metastasis Secondary to Prostate Cancer: An Unusual Presentation

Kapur

Xiao

2014

World J Oncol

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Prostate cancer is mostly known to metastasize to the bony skeleton. Soft tissue metastasis involving visceral organs such as the liver, lung and brain are unusual and rare manifestations of this cancer. However, with better treatment modalities and increased survival, the incidence of these unusual presentations, seems to have risen in the last few years. Prostate cancer is rarely known to metastasize to the orbit. Although cases of bony metastasis involving the orbit have been reported, soft tissue metastasis involving the orbit is a very rare presentation. Most soft tissue metastasis to the orbit involves the uveal tract, with prostate cancer being the most common primary cancer to metastasize to the iris (uveal tract). Our paper highlights a case of extraconal orbital soft tissue metastasis secondary to prostate cancer, an extremely rare presentation. Patient was started on combined androgen blockade therapy. Three-month repeat MRI orbit showed that the extraconal orbital mass had decreased in size significantly. His clinical symptoms have resolved at the time of this report. To our knowledge, this is the first reported case of its kind.

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“…It was reported that breast cancer (1), prostate cancer (2), adenoid cystic carcinoma of parotid gland (3), lung cancer (4), merkel cell carcinoma (5), esophageal adenocarcinoma (6), gastric cancer (7), endometrial cancer (8), Ewing sarcoma (9) and cervical cancer (10) metastasized to iris.…”

Section: Introductionmentioning

confidence: 99%

The MRIi Findings of Iris Metastasis in Patients with Breast Cancer

Mutlu

Akca²,

Büyükçelik³

et al. 2012

Acta Inform Med

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Breast cancer and lung cancer are the most common tumors that metastasize to iris. The metastasis of iris was generally diagnosed on ophthalmologic examination. In this case, we reported iris metastasis of patients with adenocarcinoma of breast cancer and MRI findings. We report a case of a 51-year-old. She was diagnosed breast cancer two years ago. After adjuvant chemotherapy, radiotherapy and trastuzumab, she was admitted to hospital with the complaints of headache on February 2012. The magnetic resonance imaging (MRI ) revealed multiple brain metastasis. Whole brain radiotherapy and palliative chemotherapy were applied to the patients. In follow-up, on ophthalmological examination, there was a solid lesion on iris. The orbital MRI was performed and it revealed the thickness on iris of left eye. After diagnostic procedure final pathological rewiev reported that invasive ductal carcinom metastasis. Iris metastasis may be considered by MRI findings following: The thickness on iris and contrast enhanced lesion. This reason may be resulted that the fine niddle aspiration biopsy for diagnosis of iris metastasis is not need.

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Prostatic carcinoma bilateral iris metastases

Cited by 9 publications

References 13 publications

A Rare Case of Prostate Carcinoma Metastasis in the Orbital Apex

A Rare Case of Prostate Carcinoma Metastasis in the Orbital Apex

Extraconal Orbital Soft Tissue Metastasis Secondary to Prostate Cancer: An Unusual Presentation

The MRIi Findings of Iris Metastasis in Patients with Breast Cancer

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