Protective Effect of Some Essential Oils Against Gamma-Radiation Damages in Tetrahymena pyriformis Exposed to Cobalt-60 Source

Potential effect of fruit and flower extracts of Arbutus unedo L. on Tetrahymena pyriformis exposed to a cobalt-60 source

“…Various plant extracts have been tested for their antioxidant properties and ability to protect against the harmful effects of radiation (El-Shawi et al 2023;Wu et al 2023). In another study by Ziyadi et al (2022a), the protective effects of certain pure essential oils (Rosmarinus officinalis, Origanum compactum, Lavandula angustifolia, and Eucalyptus globulus) on T. pyriformis against irradiation were evaluated. In this study, we assessed the ability of strawberry tree extracts from the El Harcha region of Morocco to protect T. pyriformis against the effects of radiation.…”

“…Numerous studies have demonstrated the benefits of using specific plant extracts and natural products as radioprotectants in experimental models (Dowlath et al 2021). In comparison, using non-toxic concentrations of pure essential oils (5 μg/mL for R. officinalis and E. globulus and 10 μg/mL for O. compactum and L. angustifolia) in the culture of T. pyriformis exposed to 60 Co at 20 cGy/h restored over 90% of the growth and metabolic enzyme activities (Ziyadi et al 2022a).…”

“…In this context, protection against these IR-induced cellular perturbations by evaluating the radioprotective and antioxidant effects of natural plants known for their therapeutic virtues will be an interesting area of research (Ziyadi et al 2022a). Therefore, this study aimed to evaluate the ability of aqueous and ethanolic extracts of the two plant parts of A. unedo (flowers and fruits) to reduce the effects observed in T. pyriformis after exposure to a 60 Co source.…”

Modulation of Ionizing Radiation-Induced Apoptosis by Taurine in Human Peripheral Blood Lymphocytes: Flow Cytometry-based Quantification

“…However, radiotherapy can negatively impact neighboring healthy tissues, leading to the necessitation of dose limitation to minimize harm. Accordingly, the utilization of radiation sensitizers, mitigators, or protectors with biological properties can overcome this limitation and reduce the adverse effects of radiation on healthy tissues while maintaining therapeutic effectiveness against tumors [ 2 , 3 ]. Lymphocytopenia, a common side effect of radiotherapy in cancer patients, can be misleading when evaluating the response to cancer treatment as an unfavorable prognostic marker [ 4 ].…”