Protective Role and Antioxidant Activity of Aqueous Extract of Rosmarinus Officinalis Against Trichloroacetate-Induced Toxicity in Liver of Male Rats

Abozid, M. M.; Farid, Hoda E. A.

doi:10.22159/ajpcr.2018.v11i6.25353

Cited by 2 publications

(1 citation statement)

References 35 publications

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“…50 g of leaves powder were extracted for 3 h in 500 ml of the sterilized distilled water using the Soxhlet device, and the source of heating was a boiling water bath 100°C. The leaf extract solution was then evaporated at 45°C using a rotary evaporator, and the resultant crude extract was frozen at −20°C until use to prepare the required concentration of 1 g/ml [27,28].…”

Section: Preparation Of Aqueous Extract Of Rosemarymentioning

confidence: 99%

Estimation the Antibacterial Effect of Curcumin and Rosemary Among Patients With Dental Caries in Vitro

Al-Sharifi¹,

Al-Mahmood²,

Al-Mahmood³

2019

Asian J Pharm Clin Res

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Objective: The aim is to estimate the effect of curcumin and rosemary as antibacterial agents among dental caries cases. Methods: Samples of saliva were randomly collected from 40 patients in Al-Furat General Hospital who attended the hospital from July to September 2018. Swabs were cultured on blood agar at 37°C for 24 h and then subcultured in mannitol salt agar and trypticase soy broth at 37°C for 24 h. Different concentrations of aqueous extract curcumin solution (0.1, 0.3, 0.5, and 1 mg/ml) and rosemary solution (1 g/ml) were prepared and added to the bacterial culture. Later, minimum inhibition zones of the bacterial cultures were determined. Results: The results showed that there were 25 cases of Streptococcus mutans, 10 cases of Staphylococcus aureus, 3 cases of anaerobic bacteria, and 2 cases of normal flora among 40 culturing swabs of bacteria. Aqueous extract of curcumin showed antibacterial effect with concentrations (0.1, 0.3, 0.5, and 1 mg/ml) against oral bacteria; nevertheless, these bacteria were resistant to the aqueous extract of rosemary with concentration 1 g/ml. Conclusion: It can be concluded that curcumin can be an effective antibacterial agent against dental caries disease and its effect increases positively in relation to its concentration. On the other hand, rosemary with 1 g/ml concentration did not show any effect on oral bacteria.

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Section: Preparation Of Aqueous Extract Of Rosemarymentioning

confidence: 99%

Estimation the Antibacterial Effect of Curcumin and Rosemary Among Patients With Dental Caries in Vitro

Al-Sharifi¹,

Al-Mahmood²,

Al-Mahmood³

2019

Asian J Pharm Clin Res

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Ethnobotanical survey and scientific validation of liver-healing plants in northeastern Morocco

Bencheikh,

Elbouzidi,

Baraich

et al. 2024

Front. Pharmacol.

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IntroductionLiver diseases represent a significant global health challenge, with primary causes including excessive alcohol consumption, infections, chemotherapy, and autoimmune disorders. Medicinal plants, due to their natural bioactive compounds, hold promise for developing effective treatments and preventive measures against liver ailments. This study aimed to document the use of herbal remedies in northeastern Morocco for liver diseases and correlate these uses with scientific evidence through a bibliometric analysis.MethodsAn ethnobotanical survey was conducted in remote communities of northeastern Morocco from October 2020 to January 2022. A total of 189 informants were interviewed using semi-structured questionnaires to gather information on local medicinal plants used for liver ailments. The data were analyzed using four ethnobotanical quantitative indices: use value (UV), familial use value (FUV), informant consensus factor (ICF), and fidelity level (FL). Additionally, a bibliometric analysis was performed to evaluate the scientific support for the ethnopharmacological uses documented.ResultsThe survey identified 45 plant species from 26 different families used in the treatment of liver diseases. The most frequently utilized species were Cuminum cyminum L. (UV = 0.1065), Allium sativum L. (UV = 0.1015), Salvia officinalis L. (UV = 0.0761), Asparagus officinalis L. (UV = 0.0558), and Ziziphus lotus (L.) Lam. (UV = 0.0457). The Apiaceae family showed the highest familial use value (FUV = 0.1066), followed by Alliaceae (FUV = 0.1015). Liver congestion had the highest informant consensus factor (ICF = 0.83), followed by hepatic colic (ICF = 0.80). Bibliometric analysis revealed that 61% of the plants identified had documented pharmacological effects related to liver health.DiscussionThe study demonstrates that traditional knowledge in northeastern Morocco encompasses a rich diversity of medicinal plants used to treat liver diseases. The high ICF values indicate a strong consensus among informants on the efficacy of these remedies. The correlation between ethnopharmacological use and scientific validation for a significant portion of these plants suggests their potential as reliable therapeutic agents for liver conditions. However, further scientific investigations are necessary to confirm their efficacy and safety in clinical settings. This research contributes valuable information for future studies on the therapeutic potential of these plants.ConclusionThis ethnobotanical survey provides a comprehensive database of medicinal plants used in northeastern Morocco for liver diseases. The findings highlight the potential of these plants in developing novel treatments for hepatic conditions, although further research is essential to substantiate their therapeutic claims.

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Protective Role and Antioxidant Activity of Aqueous Extract of Rosmarinus Officinalis Against Trichloroacetate-Induced Toxicity in Liver of Male Rats

Cited by 2 publications

References 35 publications

Estimation the Antibacterial Effect of Curcumin and Rosemary Among Patients With Dental Caries in Vitro

Estimation the Antibacterial Effect of Curcumin and Rosemary Among Patients With Dental Caries in Vitro

Ethnobotanical survey and scientific validation of liver-healing plants in northeastern Morocco

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