Protective role of Eclipta alba L. extract against ethinylestradiol induced genotoxic damage in cultured human lymphocytes

Siddique, Yasir Hasan; Ara, Gulshan; Beg, Tanveer; Faisal, Mohammad; Afzal, Muhammad

doi:10.4081/ams.2011.e4

Cited by 3 publications

(2 citation statements)

References 21 publications

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“…It is also a genotoxic and a tumor initiating agent. The treatment of 10 μ M of ethinylestradiol along with 1.02 × 10 −4 , 2.125 × 10 −4 , 3.15 × 10 −4 , and 4.17 × 10 −4 g/mL acetone extract of E. alba leaves resulted in a significant dose-dependent decrease in the genotoxic effects induced by the treatment of 10 μ M of ethinylestradiol in cultured human lymphocytes [ 114 ].…”

Section: Pharmacological Activity Reportsmentioning

confidence: 99%

Ethnopharmacological Significance of Eclipta alba (L.) Hassk. (Asteraceae)

Jahan

Al-Nahain

Majumder

et al. 2014

International Scholarly Research Notices

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Eclipta alba can be found growing wild in fallow lands of Bangladesh where it is considered as a weed by farmers. Traditional medicinal systems of the Indian subcontinent countries as well as tribal practitioners consider the plant to have diverse medicinal values and use it commonly for treatment of gastrointestinal disorders, respiratory tract disorders (including asthma), fever, hair loss and graying of hair, liver disorders (including jaundice), skin disorders, spleen enlargement, and cuts and wounds. The plant has several phytoconstituents like wedelolactone, eclalbasaponins, ursolic acid, oleanolic acid, luteolin, and apigenin. Pharmacological activities of plant extracts and individual phytoconstituents have revealed anticancer, hepatoprotective, snake venom neutralizing, anti-inflammatory, and antimicrobial properties. Phytoconstituents like wedelolactone and ursolic and oleanolic acids as well as luteolin and apigenin can form the basis of new drugs against cancer, arthritis, gastrointestinal disorders, skin diseases, and liver disorders.

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Section: Pharmacological Activity Reportsmentioning

confidence: 99%

Ethnopharmacological Significance of Eclipta alba (L.) Hassk. (Asteraceae)

Jahan

Al-Nahain

Majumder

et al. 2014

International Scholarly Research Notices

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“…The herb is rich in nutrients and pentacyclic triterpenes [2]. It can be used for improving memory [3], antibacterial and antifungal [4], antigenotoxic [5], antitumor [6], anti-stress [7], and antiproliferative [8].…”

Section: Introductionmentioning

confidence: 99%

Experimental investigation of the performance of a solar dryer integrated with solid desiccant coloums using water based solar collector for medicinal herb

Yahya

Hasibuan

Sundari

et al. 2021

IJPEDS

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This study is concerned with the analyses of performance on a solar dryer integrated with solid desiccant coloums using water based solar collector. The dryer consists of a solar water collector, two solid desiccant coloums, a water storage tank, two heat exchangers, an air heater, and a drying chamber. The dryer decreased the <em>Centella asiatica</em> L moisture content from 88.3% (wb) to 15.9% (wb) within 12 hours, with an average temperature and relative humidity of 45.4°C and 25.8%, respectively. The rate of moisture evaporation and the specific moisture evaporation rate were in the range of 0.001-1.762kg/h and 0.02-0.482 kg/kWh, with 0.594kg/h and 0.169kg/kWh in average values, respectively. The dryer efficiency was in the range of 0.62%-30.4%, with 15.4% in average value. The energy required for moisture evaporation and total energy input to the dryer were in the range of 26.9-1132.2W and 3638.0-4329.7W, with 601.8 W and 3967.4 W in average values, respectively. The efficiency of collector and the heat exchanger effectiveness were in the range of 38.1-50.5% and 65.1-79.7%, with 45.0% and 73.0% in average values, respectively. The result shows that the dryer is suitable for drying <em>Centella asiatica </em>L, this is due to the low temperature of drying air and high moisture evaporation rate.

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