Protein binding protection in combination with DNA masking for sensitive and reliable transcription factor detection

Xu, Xiaowen; Wang, Lei; Zhu, Desong; Yan, Wang; Jiang, Wei

doi:10.1016/j.talanta.2018.04.047

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Overview Of Rapid Diagnosis By Poct Platforms1

Poct Platforms Based On Nucleic Acid Amplification Technologies1

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Cited by 10 publications

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“…At present, kinds of isothermal amplification technologies that can be implemented in the POCT diagnostic platform, such as loop-mediated isothermal amplification (LAMP) [42] , [43] , [44] , [45] , [46] , [47] , recombinase polymerase amplification (RPA) [48] , [49] , [50] , [51] , [52] , rolling circle amplification (RCA) [53] , [54] , [55] , [56] , [57] , and nicking enzyme-assisted reaction (NEAR) [58] , [59] , [60] , [61] ( Fig. 1 ).…”

Section: Overview Of Rapid Diagnosis By Poct Platformsmentioning

confidence: 99%

“…A total of 106 samples, including 41 SARS-CoV-2 and 9 samples positive for other respiratory viruses, were tested by this assay, which reported a concordance 100% result with RT-PCR. This one-step sandwich hybridization assay can test as low as 1 copy/μL of N and spike ( S ) genes within 2 h. This approach allows testing kits to be allocated to outbreak areas broadly, as well as remote regions where laboratory facilities are insufficient, which particularly; is beneficial for some developing countries [ 56 , 57 ].…”

Section: Poct Platforms Based On Nucleic Acid Amplification Technologiesmentioning

confidence: 99%

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