Protein contact dermatitis with positive RAST caused by bovine blood and amniotic fluid

Atopic symptoms among California veterinarians

“…In a study by Lutsky et al [1985], the prevalence of asthma in veterinarians was almost three times (16%) the prevalence in controls (6%). According to casereports, veterinarians have complained of hand dermatitis or urticaria associated with animal fluid and skin contact [Prahl and Roed-Petersen, 1979;Hjorth and Roed-Petersen, 1980;Rudzki et al, 1982;Degreff et al, 1984;Falk et al, 1985;Kalveram et al, 1986;Roger et al, 1995]. Fourteen percent of California veterinarians and 16% of Kansas veterinarians have reported recurrent or persistent hand/forearm dermatitis during the past 12 months [Susitaival et al, 2001;Tauscher and Belsito, 2002].…”

‘Lambing ears’: a blistering disorder affecting farmers at lambing time

“…Thus the only unique factor at lambing time would seem to be the amniotic fluid, sac and placenta. It is known that bovine amniotic fluid (and blood) can cause contact dermatitis and/or can result in a positive radioallergosorbent test, 5,6 and as indoor lambing progresses the straw bedding becomes increasingly contaminated with amniotic fluid.…”

Animals

“…from various other mammalian species and birds has been reported to cause PCD or CU or other skin symptoms (Epstein 1948;Schneider et al 1960;Cockroft et al 1981;Göransson 1981;van Ketel and van Diggelen 1982;van der Mark 1983;Degreff et al 1984;Agrup and Sjöstedt 1985;Kalveram et al 1986;Camarasa 1986;Prahl and Roed-Petersen 1979;Hjorth and Roed-Petersen 1980;Hansen and Petersen 1989;Aoyama et al 1992;Susitaival et al 1995;Valsecchi et al 2003;Herzinger et al 2005;Buckle and Devos 2007;Swiderska-Kiełbik et al 2011;Renström et al 2011;Polovic et al 2013). Also, delayed allergy to animal proteins has been documented in several reports (Epstein 1948;Roth 1968;Malanin and Kalimo 1992;Susitaival et al 1995;Timmer and Coenraads 1996;Kanerva and Estlander 1997;Mahler et al 1998;Ljubojevic et al 2007).…”

“…CU or PCD from animal proteins is often accompanied by respiratory symptoms, and the respiratory symptoms may precede skin symptoms by years (Aoyama et al 1992;Nienhaus et al 2005;Spiewak et al 2000;Spiewak 2004;Barbuzza et al 2009;Helaskoski et al 2017;Muzembo et al 2014). Skin tests for immediate allergy (e.g., SPT) or specific IgE have been positive with animal dander, hair, amniotic fluid, serum, blood, organs, milk, and saliva (Rudzki 1975;Prahl and Roed-Petersen 1979;Hjorth and Roed-Petersen 1980;Slovak and Hill 1981;Degreff et al 1984;Agrup and Sjöstedt 1985;Falk et al 1985;Kalveram et al 1986;Weissenbach et al 1988;Karches and Fuchs 1993;Buckle and Devos 2007;Valsecchi et al 2003). Cross sensitivity is common, especially with mammalian serum albumins, most commonly between dog, cat, pig, and horse (Alvarez-Perea et al 2014).…”