2024
DOI: 10.1002/mabi.202400338
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Proteins‐Based Nanoparticles for Benznidazole Enteric Delivery

Victor A. Pilicita,
Ana S. Sonzogni,
Mariana Allasia
et al.

Abstract: Chagas disease, caused by Trypanosoma cruzi (T. cruzi), affects millions worldwide, particularly in Latin America. Despite its prevalence, treatment options remain limited. Current drugs, such as benznidazole, cause adverse effects possibly due to ineffective administration. In this context, nanoparticles offer a promising solution to target and control drug delivery by leading the effector site and minimizing side effects. This article focuses on zein‐casein‐based nanoparticles (Bioparticles, BP) coated with … Show more

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