“…This data suggested that the beads were in the micro-millimeter scale. The range was comparable to cellulose beads used in protein separation, as previously reported by Li et al (2014). These authors studied the protein separation and purification by expanded bead adsorption, and cellulose beads with a particle size distribution of 80 to 165 μm were used as the separation media.…”
The conversion of lignocellulosic biomass into fine chemicals and polymers has been gaining attention recently. Regenerated lignocellulose beads (RLBs) were prepared by an emulsification/precipitation technique, using wheat straw as a raw material and [Bmim]Cl as a solvent. The morphology and properties of the obtained beads were characterized. The RLBs were perfectly spherical, with a porous microstructure, and had a huge specific surface area (142.4 m 2 /g). Their components were similar to that of wheat straw; however some chemical and crystal changes of these components occurred during the preparation process. Eighty percent of the beads were in the size range between 24.4 to 149.6 μm, and the mean particle size was 84.7 μm. Furthermore, the beads possessed good thermostability in the temperature range between ambient temperature and 200 °C. This work demonstrated the feasibility of the production of RLBs using lignocellulosic biomass and provided a new direction for high-valued utilization of lignocellulosic agricultural residues.
“…This data suggested that the beads were in the micro-millimeter scale. The range was comparable to cellulose beads used in protein separation, as previously reported by Li et al (2014). These authors studied the protein separation and purification by expanded bead adsorption, and cellulose beads with a particle size distribution of 80 to 165 μm were used as the separation media.…”
The conversion of lignocellulosic biomass into fine chemicals and polymers has been gaining attention recently. Regenerated lignocellulose beads (RLBs) were prepared by an emulsification/precipitation technique, using wheat straw as a raw material and [Bmim]Cl as a solvent. The morphology and properties of the obtained beads were characterized. The RLBs were perfectly spherical, with a porous microstructure, and had a huge specific surface area (142.4 m 2 /g). Their components were similar to that of wheat straw; however some chemical and crystal changes of these components occurred during the preparation process. Eighty percent of the beads were in the size range between 24.4 to 149.6 μm, and the mean particle size was 84.7 μm. Furthermore, the beads possessed good thermostability in the temperature range between ambient temperature and 200 °C. This work demonstrated the feasibility of the production of RLBs using lignocellulosic biomass and provided a new direction for high-valued utilization of lignocellulosic agricultural residues.
“…EBA is an interesting idea where the core-shell adsorbent particles expand nicely in a bed without the chaotic movement of particles thanks to properly designed particle size and density distribution allowing cell debris to pass through the bed whilst the solute (proteins) are retained by the adsorbent. In principle with EBA one doesn't need previous solid/liquid separation; however some concerns remain with adsorbent capacity loss due to cell adhesion to the particle surface and dead volumes in the top of EBA columns are not good for SMB chromatographic separation [26,27].…”
“…To overcome the limitations this caused, particles with a densified core were developed, allowing linear velocities of up to 900 cm h ‐1 . Early densified resins incorporated glass or silica, while later metals such as steel or tungsten carbide were used . Several researchers have attempted to minimize unwanted interactions by modifying the adsorbent particle backbone.…”
Section: Review Of Mathematical Models Describing Eba Behaviourmentioning
confidence: 99%
“…While these modifications were found promising in academic research, they were not widely adopted by commercial resin manufacturers. An extensive overview of commercially available and custom made resins can be found in Li et al As is typical for packed bed columns, early EBA columns employed a perforated plate or mesh as flow distributor, sometimes in combinations with large, inert particles. Both designs were found to be very susceptible to fouling and difficult to clean, limiting their potential for use in the biopharma industry .…”
Section: Review Of Mathematical Models Describing Eba Behaviourmentioning
confidence: 99%
“…While these modifications were found promising in academic research, they were not widely adopted by commercial resin manufacturers. An extensive overview of commercially available and custom made resins can be found in Li et al …”
Section: Review Of Mathematical Models Describing Eba Behaviourmentioning
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
