Protocols on Safety, Efficacy, Standardization, and Documentation of Herbal Medicine

Mosihuzzaman, M.; Choudhary, M. Iqbal

doi:10.1515/iupac.80.0354

Cited by 36 publications

(27 citation statements)

References 9 publications

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“…Heavy metals contamination of herbaceous plants may be due contaminated plantation areas. Herbaceous plant grown within city areas were exposed to pollution from manufacturing activities, smoke from motor vehicles and other sources of pollution (Mosihuzzaman & Choudry 2008); (WHO 2007). Plants absorb heavy metals in contaminated water through roots or other exposed plant parts which is not equally distributed over the entire plant (Tokahuglu 2012).…”

Section: Discussionmentioning

confidence: 99%

Commercial Herbal Slimming Products: Evaluation of Heavy Metals and Microorganism Contamination at Different Batch Production

Bakar

Zin

Kechik

et al. 2017

JSKM

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Herbal-based slimming products which are consumed orally may be contaminated with heavy metals as well as microorganisms. This study aimed to evaluate the safety level of these slimming products by determining heavy metals and microbial contamination in different batch production. Six different brands of herbal-based slimming products (A, B, C, G, H and I) ppm). All 3 batches of sample A presented with the highest total daily intake of heavy metals. Bacteria were present in all the samples tested with the highest numbers in samples G, H and A followed by B, I and C. The highest number of fungi was found in product Produk pelangsingan berasaskan herba yang diambil secara oral boleh dicemari logam berat dan juga mikroorganisma. Tujuan kajian ini adalah untuk menilai tahap keselamatan produk pelangsingan ini dengan penentuan tahap pencemaran logam berat dan mikroorganisma di dalam sampel pada kelompok pengeluaran yang berbeza. Sebanyak enam jenama produk pelangsingan berasaskan herba berbeza (A, B, C, G, H dan I) dengan kelompok pengeluaran berbeza (1, 2 dan 3) dikaji (n = 18). Penentuan lima logam berat Arsenik, Kadmium, Kromium, Kuprum dan Zink ditentukan dengan menggunakan Plasma Gandingan Induktif -Spektrometri Jisim (ICP-MS

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Section: Discussionmentioning

confidence: 99%

Commercial Herbal Slimming Products: Evaluation of Heavy Metals and Microorganism Contamination at Different Batch Production

Bakar

Zin

Kechik

et al. 2017

JSKM

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“…Herb extracts are often easier to digest and usually cause a less digestive upset, though even extracts can cause a feeling of nausea or fullness to occur in some cases. Adverse drug reactions, allergic reactions, drug interactions, herb-drug interactions, contamination of the drug, false authentication of the drug are some of the other challenges that come into consideration when spoke about herbal cosmetics [93,94].…”

Section: Toxicity Of Traditional Herbal Drugsmentioning

confidence: 99%

Challenges in Formulating Herbal Cosmetics

D.k.

Jain

2018

Int J App Pharm

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The herbal cosmetics are prepared by phytochemicals that occur in a variety of botanical sources, that influences the physiology of skin and provide nutrients that are necessary for the healthy skin or hair. These products are utilized for daily purposes, which include herbal shampoo, herbal conditioner, herbal face wash, herbal soap, etc. These products are classified as a different category by regulatory agencies. However, guidelines of these certifying agencies have no harmonization, and many cosmetic industries prepare and package these formulations in an irrationalway. Many cosmetic products have natural products in their formulation that perform a specific biological function, but these products should be evaluated on their toxicological and efficacy aspects. The contribution of developing countries is very poor in global herbal business because of lack of standardization measures and quality control. The lack of safety and efficacy data on herbal cosmetics renders it difficult to meet the criteria needed for supporting its use worldwide. This review article discusses challenges related to regulatory status, quality control, standardization, certification, drug processing and the opportunities for herbal cosmetics in local as well as the global scenario. The search criteria used in the present review were the keywords mentioned in the manuscript and articles from major scientific resources were cited. The articles from 1952 to 2018 were specifically referred, but few references from 19 century were also cited to support the prevalence of scientific principles in the development of herbal cosmetics in the ancient era.

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“…Some advanced methods like chromatographic, spectrophotometric or combination of these, polarography, electrophoresis, and use of molecular biomarkers are currently used in standardization of herbal drugs. [21][22][23][24][25][26] The formulation was powder in nature and has characteristic odour and colour. Standardization of polyherbal formulation as per pharmacopeia was carried out based on the physiochemical parameters and the DiaKure passed all the tests.…”

Section: Conflict Of Interestmentioning

confidence: 99%

Preliminary Pharmacognostical and Phytochemical Screening of DiaKure–A Polyherbal Antidiabetic Formulation

Tk¹,

Celine²,

Tomy³

et al. 2016

JYP

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Background: Diakure is an indigenously prepared hypoglycemic polyherbal formulation, containing mixture of Vetiveria zizanoides (root), Hemidesmus indicus (rhizome), Strychnos potatorum (seed), Salacia reticulata (bark), Holarhena antidysenterica (seed), Cassia auriculata (bark), Trigonella graecum (seed) and Acacia catechu (bark) and each individual herb has scientific background in treating diabetes. This study aimed to perform pharmacognostical evaluation, preliminary phytochemical evaluation, standardization, heavy metal analysis, pesticidal residual analysis and antimicrobial assay of DiaKure. Materials and Methods: 100 g of the powder mixture of all eight herbs mentioned above was boiled with 900 ml water for 30 min to produce the polyherbal mixture and this mixture was used for performing various tests. Results: Organoleptic characters and macroscopic characters such as colour, odour, taste, size and shape are evaluated under pharmacognostical evaluations and ash values, extractive values and loss on drying are considered under standardisation parameters and are reported. Phytochemical screening of the extract revealed the presence of alkaloids, tannins, saponins, flavonoids, steroids, glycoside and sugars. The formulation has normal limits of heavy metal and pesticidal residue. Also, the aqueous mixture, during its antimicrobial assay, does not exhibit any antibacterial or anti-fungal activities. Conclusion: The result of this study validates the use of aqueous extract of DiaKure in ethnomedicine, favouring the isolation of antidiabetic agents from the extract of DiaKure. Since the study was conducted in a controlled and authenticated manner, all the evaluation measures used in the study can be used for the standardization of the above-said formulation.

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Protocols on Safety, Efficacy, Standardization, and Documentation of Herbal Medicine

Cited by 36 publications

References 9 publications

Commercial Herbal Slimming Products: Evaluation of Heavy Metals and Microorganism Contamination at Different Batch Production

Commercial Herbal Slimming Products: Evaluation of Heavy Metals and Microorganism Contamination at Different Batch Production

Challenges in Formulating Herbal Cosmetics

Preliminary Pharmacognostical and Phytochemical Screening of DiaKure–A Polyherbal Antidiabetic Formulation

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