Proxy and self-reported Quality of Life in adults with intellectual disabilities: Impact of psychiatric symptoms, problem behaviour, psychotropic medication and unmet needs

Koch, A.; Vogel, Anke; Becker, Thomas; Salize, Hans-Joachim; Voß, Elke; Werner, Amelie; Arnold, Katrin; Schützwohl, Matthias

doi:10.1016/j.ridd.2015.07.022

Cited by 56 publications

(41 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The association of challenging behaviors, such as irritability and lethargy with mental well-being, is in line with previous studies. 15,16 In addition, during a previous discontinuation study, we found an increase in the severity of individually chosen target behaviors as measured with a visual analog scale at the time point of scheduled discontinuation in those with incomplete discontinuation of the antipsychotic drugs and no change in those with complete discontinuation. 5 Furthermore, McNamara et al 23 found an increase in aggression and irritability in those who discontinued risperidone.…”

Section: Discussionmentioning

confidence: 62%

“…11 Challenging behaviors and the side effects of antipsychotic drug use can affect health-related quality of life. [12][13][14][15][16] Health-related quality of life describes the health status of a person comprehensively. Both physical and emotional well-being are considered, as well as the role limitations caused by physical or emotional problems (ie, the ability to participate and perform normal daily tasks and activities), social functioning (the ability to participate in normal social activities), pain, and general health.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Changes in Health‐Related Quality of Life in People With Intellectual Disabilities Who Discontinue Long‐Term Used Antipsychotic Drugs for Challenging Behaviors

Ramerman

Hoekstra

Kuijper

2018

The Journal of Clinical Pharma

View full text Add to dashboard Cite

Health-related quality of life in people with intellectual disabilities can be affected by challenging behaviors and side effects of antipsychotics. The aim of this study was to evaluate the effect of discontinuation antipsychotic drugs on health-related quality of life, including data from 2 discontinuation trials: an open-label trial of various antipsychotic drugs and a double-blind trial of risperidone. In both studies, antipsychotics were discontinued in 14 weeks, with steps of 12.5% of the baseline dosage every 2 weeks. Health-related quality of life was measured at baseline and at 16 weeks, and 40 weeks after baseline, by means of the RAND-36 (domains on physical well-being, role limitations caused by physical or emotional problems, vitality, pain, mental well-being, social functioning, general health, and changes in health). Participants who had completely discontinued antipsychotics according to the scheduled discontinuation and were still free of use at 40 weeks were compared with those who had incompletely discontinued. Physical well-being showed an increase in the group that had achieved complete discontinuation. Social functioning showed a decrease in the group that incompletely discontinued, which recovered at follow-up. Mental well-being decreased at 16 weeks but recovered at follow-up, regardless of complete or incomplete discontinuation. To conclude, discontinuation of antipsychotics had a positive effect on physical well-being when complete discontinuation was possible. When complete discontinuation was not possible, there was a negative effect on health-related quality-of-life domains. However, none of the unfavorable effects were irreversible.

show abstract

Section: Discussionmentioning

confidence: 62%

mentioning

confidence: 99%

Changes in Health‐Related Quality of Life in People With Intellectual Disabilities Who Discontinue Long‐Term Used Antipsychotic Drugs for Challenging Behaviors

Ramerman

Hoekstra

Kuijper

2018

The Journal of Clinical Pharma

View full text Add to dashboard Cite

show abstract

“…Se ha encontrado la tendencia de valorar la calidad de vida en las PCDI únicamente desde la óptica del cuidador, subestimando la opinión de la propia PCDI (2), situación probablemente generada por las diferencias de opinión entre los cuidadores y las PCDI, aun tratándose de un mismo contexto socio-familiar, reportando además que las PCDI suelen responder en forma positiva, desconociendo aún la causa de éstas diferencias (3,4). Nuestra experiencia confirma que las PCDI pueden informar de manera real la percepción sobre sus condiciones de vida, más aún, las últimas investigaciones sobre autodeterminación indican que ellos tienen la capacidad para opinar, tomar decisiones y vivir una vida independiente (5).…”

Section: Sres Editoresunclassified

Valoración de la calidad de vida desde la autopercepción de la persona con discapacidad intelectual: avance preliminar.

Carbajal¹,

Coronel²

2018

Rev Neuropsiquiatr

View full text Add to dashboard Cite

show abstract

“…Si bien algunos estudios han encontrado moderada coincidencia entre las respuestas de los cuidadores y de las PCDI (Córdoba-Andrade, Henao & Verdugo, 2016;Golubović & Škrbić, 2013), la gran mayoría ha identificado importantes diferencias entre una y otra perspectiva (Balboni, Coscarelli, Giunti & Schalock, 2013;Claes et al, 2012;Emerson, Felce & Stancliffe, 2013;Simões & Santos, 2016). Más aun, se ha observado que los factores sociodemográficos asociados a la calidad de vida se relacionan de distinta manera con ambos tipos de información: la brindada por el cuidador y la brindada por la PCDI (Koch et al, 2015).…”

Section: Introductionunclassified

Factores asociados a la calidad de vida en personas con discapacidad intelectual

Carbajal

2019

Interd

View full text Add to dashboard Cite

La calidad de vida es un aspecto central de la nueva conceptualización de la discapacidad intelectual, siendo necesario el estudio de variables ambientales. Para ello, se analizaron los factores asociados a la calidad de vida en 105 personas con discapacidad intelectual (professional career development Institute-PCDI-), procedentes de tres instituciones públicas de Lima-Perú. El instrumento utilizado fue la Escala Integral de Calidad de Vida (Verdugo, Arias, & Gómez, 2009), conformada por dos escalas: Calidad de Vida Objetiva, dirigida al cuidador y Calidad de Vida Subjetiva dirigida a la PCDI, ambas aplicadas mediante una entrevista. Para establecer la asociación entre las variables sociodemográficas (edad, sexo, trabajo, condición socioeconómica y tipo de familia) con la calidad de vida se realizaron análisis correlacionales utilizando técnicas bivariadas y de regresión. Las PCDI tuvieron edades comprendidas entre 15 y 45 años, siendo 39 (37%) mujeres y 66

show abstract

Proxy and self-reported Quality of Life in adults with intellectual disabilities: Impact of psychiatric symptoms, problem behaviour, psychotropic medication and unmet needs

Cited by 56 publications

References 35 publications

Changes in Health‐Related Quality of Life in People With Intellectual Disabilities Who Discontinue Long‐Term Used Antipsychotic Drugs for Challenging Behaviors

Changes in Health‐Related Quality of Life in People With Intellectual Disabilities Who Discontinue Long‐Term Used Antipsychotic Drugs for Challenging Behaviors

Valoración de la calidad de vida desde la autopercepción de la persona con discapacidad intelectual: avance preliminar.

Factores asociados a la calidad de vida en personas con discapacidad intelectual

Contact Info

Product

Resources

About