Prunus mahaleb L. fruit extracts: a novel source for natural food pigments

Gerardi, C.; Tommasi, Noemi; Albano, Clara; Blando, Federica; Rescio, Leonardo; Pinthus, Eli J.; Mita, Giovanni

doi:10.1007/s00217-015-2495-x

Cited by 42 publications

(34 citation statements)

References 59 publications

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“…Antioxidant Assay Kit was purchased from Cayman Chemicals (Ann Arbor, MI, USA). The composition of MCFE used had been recently reported . DSS (36–50 KDa) was purchased from MP Biomedicals, Ontario, USA.…”

Section: Methodsmentioning

confidence: 99%

“…The composition of MCFE used had been recently reported. [14] DSS (36-50 KDa) was purchased from MP Biomedicals, Ontario, USA. The list of primary antibodies and dilutions used for used for immunoblotting analysis are reported in Table S1, Supporting Information.…”

Section: Reagentsmentioning

confidence: 99%

“…is a neglected species, well adapted to marginal soils mainly used as cherry‐rootstock and it produces cherry‐like dark purple drupes that have a bitter taste and are rich in potentially beneficial components (anthocyanins, flavonols, and coumarins). Antioxidant capacity, pro‐apoptotic and anti‐inflammatory effects of a mahaleb concentrated fruit extract (mfce) were recently demonstrated by in vitro cell‐based assay, nevertheless MCFE ability to improve RedOx status via this mechanism has not been investigated yet. As polyphenols efficacy as Nrf2 inducer has been recently reviewed, therefore, we assumed that MCFE intake, owing to the presence of potentially beneficial molecules, would improve cytoprotective defenses and mitochondrial function via the activation of the Nrf2 pathway.…”

Section: Introductionmentioning

confidence: 99%

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Prunus Mahaleb Fruit Extract Prevents Chemically Induced Colitis and Enhances Mitochondrial Oxidative Metabolism via the Activation of the Nrf2 Pathway

Ferramosca

Treppiccione

Giacomo

et al. 2019

Molecular Nutrition Food Res

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Scope Polyphenols exhibit their antioxidant activity downstream the activation of the nuclear factor erythroid 2‐related factor 2 pathway (Nrf2), but the connection between lipid metabolism and the Nrf2 pathway is still unknown. Flavonoid‐rich concentrated extract from Prunus mahaleb (mahaleb concentrated fruit extract; MCFE) may act on oxido‐reductive homeostasis and hepatic lipid metabolism via Nrf2. Methods & Results MCFE ability to enhance the activity of Nrf2‐mediated antioxidant/detoxifying enzymes is investigated in liver and colon of BALB/c mice. After a 4‐week supplementation, macroscopic, histological, and biochemical signs of colitis are examined in mouse colon pulsed with 5% (w/v) dextran sodium sulfate (DSS). Untreated or DSS‐supplemented mice are used as negative or positive control. MCFE effect on liver lipid metabolism and its possible link with the Nrf2 pathway is investigated. MCFE intake increases antioxidant defenses in mice colon and its pretreatment blunts pathological signs of colitis, as compared to positive control. In the liver, the increase in antioxidant defenses is associated with enhanced oxidative metabolism and with higher levels of peroxisome proliferator‐activated receptor gamma coactivator 1‐alpha (PGC‐1α) and of hemeoxygenase‐1 (HO‐1), in comparison with negative controls. Conclusion Cytoprotective and hypolipidemic effect produced by MCFE intake results, at least in part, by the activation of the Nrf2 pathway.

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Section: Methodsmentioning

confidence: 99%

Section: Reagentsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Prunus Mahaleb Fruit Extract Prevents Chemically Induced Colitis and Enhances Mitochondrial Oxidative Metabolism via the Activation of the Nrf2 Pathway

Ferramosca

Treppiccione

Giacomo

et al. 2019

Molecular Nutrition Food Res

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“…What is more, FT-IR spectra of PMF and its chemical composition can be found in the literature, while FT-IR spectra and chemical composition of RTF and JFL dye extracts were specified for the first time in this study, to the best of our knowledge. 41…”

Section: Ft-ir Measurementsmentioning

confidence: 99%

St. Lucie cherry, yellow jasmine, and madder berries as novel natural sensitizers for dye‐sensitized solar cells

et al. 2019

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Summary Natural dyes extracted from fruits, vegetables, flowers, and leaves are considered as promising alternative sensitizers to replace synthetic dyes for dye‐sensitized solar cells (DSSCs). Generally, solar activity of natural dyes stem from anthocyanin pigment. Carbonyl, carboxyl, and hydroxyl groups present in the anthocyanin molecule improve the adsorption ability of dye on TiO2 and therefore facilitate charge transfer. Here, for the first time, novel natural dyes extracted from St. Lucie cherry, yellow jasmine, and madder berries are reported to act as sensitizer in DSSCs. These novel natural dye extracts are prepared by dissolving related fruits in ethanol. The ingredient of the dyes is identified by FT‐IR spectroscopy. Accordingly, FT‐IR spectrum reveals that novel natural dye extracts exhibit all the characteristic peaks of anthocyanin pigment. Specifically, St. Lucie cherry consists of more distinct carbonyl group than other sources. Also, photoanodes composed of three TiO2 layers are prepared by using a spin‐coating method. Then, they are immersed into natural dyes and analyzed by conducting UV‐Vis spectroscopy. Compared with bare TiO2, natural dye–loaded photoanodes demonstrate far higher absorption ability in the visible region. After fabrication of devices with different novel natural dye sensitizers, current‐voltage characteristics and electrochemical impedance spectroscopy measurements are performed. The best power conversion efficiency (PCE) of 0.19% is obtained by sensitization of St. Lucie cherry with an open‐circuit voltage (Voc) of 0.56 V, short‐circuit current density (Jsc) of 181 μA cm−2, and fill factor (FF) of 0.55. Furthermore, St. Lucie cherry–sensitized devices show the lowest charge transfer and highest recombination resistances. This result can be attributed to the obvious carbonyl group exhibited by St. Lucie cherry.

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“…After centrifugation of the slurry (10 min at 4000× g), the supernatants were collected and 1 mL of extract was further centrifuged (10 min at 15,000× g and injected into the HPLC system (Agilent 1100 series)). The identification and quantification were performed by the HPLC system equipped with a pump system, a refractive index detector (RID) for sugar analysis, and a UV/Vis detector monitoring organic acids at 210 nm onto an Aminex HPX-87H column (300 × 7.8, 9 µm) (Bio-Rad, Hercules, CA, USA), kept at 55 • C. The analytical method was the same as reported in Gerardi et al (2015) [24].…”

Section: Sugar and Organic Acid Extraction And Quantificationmentioning

confidence: 99%

Phytochemical Analysis and Antioxidant Properties in Colored Tiggiano Carrots

et al. 2018

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Abstract:The carrot (Daucus carota L.) is an important vegetable source of bioactive compounds in the human diet. In the Apulia region (Southern Italy), local farmers have domesticated colored landraces of carrots over the years, strictly related to local cults and traditions. Amongst these, an important landrace is the carrot of Saint Ippazio or the Tiggiano carrot. In the present study, we evaluated the content of carotenoids, anthocyanins, phenolic acids, sugars, organic acids, and antioxidant activity in Tiggiano carrots. Our results indicated that yellow-purple carrots have the highest levels of bioactive compounds, together with the highest antioxidant capacity compared to the yellow and cultivated orange varieties. These data point out the nutritional value of purple Tiggiano carrots and may contribute to the valorization of this typical landrace.

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Prunus mahaleb L. fruit extracts: a novel source for natural food pigments

Cited by 42 publications

References 59 publications

Prunus Mahaleb Fruit Extract Prevents Chemically Induced Colitis and Enhances Mitochondrial Oxidative Metabolism via the Activation of the Nrf2 Pathway

Prunus Mahaleb Fruit Extract Prevents Chemically Induced Colitis and Enhances Mitochondrial Oxidative Metabolism via the Activation of the Nrf2 Pathway

St. Lucie cherry, yellow jasmine, and madder berries as novel natural sensitizers for dye‐sensitized solar cells

Phytochemical Analysis and Antioxidant Properties in Colored Tiggiano Carrots

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