Pseudoaccommodation: BioComFoldversus a foldable silicone intraocular lens

Jm, Legeais; Werner, Liliana; Werner, L; Abenhaim, A; Renard, G

doi:10.1016/s0886-3350(99)80137-0

Cited by 59 publications

(30 citation statements)

References 20 publications

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“…Globe convergence under accommodative effort leads to incremental misalignment between the visual axis and measuring beam which is difficult to compensate for. Differing results have been published with both A-and B-scan devices [1,41,42]. More consistent results have been recently reported with a special laboratory set-up [57].…”

Section: Vienna Resultsmentioning

confidence: 58%

Accommodating intraocular lenses: a critical review of present and future concepts

Menapace

Findl

Kriechbaum

et al. 2006

Graefe's Arch Clin Exp Ophthalmol

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As opposed to psychophysical evaluation techniques, laser interferometry measures what shift lenses are designed to provide: axial shift on accommodative effort. While under pilocarpine some movement was recorded, no movement at all was found under near-point stimulation with any of the lenses currently marketed. In contrast, magnetic-driven active-shift lens systems carry the potential of sufficiently topping up apparent accommodation to provide for clinically useful accommodation while using conventional lens designs with proven after-cataract performance. Dual optic implants significantly increase the impact of axial optic shift. The main potential problem, however, is delayed formation of interlenticular regenerates. Lens refilling procedures offer the potential of fully restoring accommodation due to the great impact of increase in surface curvature on refractive lens power. However, various problems remain to be solved before clinical use can be envisaged, above all, again, after-cataract prevention. The concept of passive single-optic shift lenses has failed. Concomitant poor capsular bag performance makes these lenses an unacceptable trade-off. Magnet-assisted systems potentially combine clinically useful accommodation with satisfactory after-cataract performance. Dual optic lenses theoretically offer substantial accommodative potential but may allow for interlenticular after-cataract formation. Lens refilling procedures have the greatest potential for fully restoring natural accommodation, but will again require years of extensive laboratory and animal investigations before they may function in the human eye.

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Section: Vienna Resultsmentioning

confidence: 58%

Accommodating intraocular lenses: a critical review of present and future concepts

Menapace

Findl

Kriechbaum

et al. 2006

Graefe's Arch Clin Exp Ophthalmol

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“…A zoom principle accommodating IOL has been designed (BioComFold, Morcher, Stuttgart, Germany); unfortunately the anterior-posterior movement induced by accommodation is inadequate to produce the desired increase in effective power. 8,9 Animal models using a flexible silicone polymeric gel to fill the capsular bag following lens extraction have failed as a result of capsular fibrosis. 10 The most promising approach at present involves modification of the IOL optic to create multiple focal distances (multifocal IOL).…”

Section: Introductionmentioning

confidence: 99%

Prospective randomised double-masked trial of bilateral multifocal, bifocal or monofocal intraocular lenses

Leyland

Langan

Goolfee

et al. 2002

Eye

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Aims To evaluate the functional effect of bilateral implantation of two different multifocal intraocular lenses (IOL) compared with the standard monofocal IOL. Methods Sixty-nine patients were recruited into a prospective, double-masked, randomised, controlled trial at a single hospital in the United Kingdom. Sixty completed follow-up; 16 implanted with monofocal IOLs, 29 with AMO 'ARRAY' multifocal IOLs and 15 with Storz 'TRUEVISTA' bifocal IOLs. Phacoemulsification and IOL implantation was performed to a standardised technique in both eyes within a 2-month period. The main outcome measures were distance and near visual acuity, depth of field and validated assessment of subjective function (TyPE questionnaire). Results Unaided distance acuity was good, and equivalent across the three groups. Corrected distance acuity was significantly lower in the bifocal group. Patients with multifocal and bifocal IOLs could read smaller absolute print size than those in the monofocal group (P = 0.05), but at a closer reading distance such that mean unaided near acuity was equal in the three groups. Corrected near acuity was significantly higher in the monofocal control group (P Ͻ 0.05). Depth of field was increased in multifocal (P = 0.06) and bifocal (P = 0.004) groups. Overall visual satisfaction was equal in the three groups, while near visual satisfaction was higher in the multifocal group than the monofocal (P = 0.04). Spectacle independence was not seen in the monofocal group, but was achieved in 28% of multifocal IOL patients and 33% of bifocal patients (P Ͻ 0.001). Adverse symptoms such as glare and haloes were significantly more bothersome with multifocal (not bifocal) IOLs than monofocals (P = 0.01). Conclusions Multifocal and bifocal IOLs improved unaided near vision performance, with around one in three patients becoming spectacle-independent. The main adverse effect was an increased incidence of subjective glare and haloes in the multifocal IOL group.

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“…3,5,7,8,11,12,23,24 OS using pharmacological technique has been demonstrated to be 0.0870.26 mm for polymethyl methacryclate (PMMA), 5 0.4270.46 mm for hydrogel IOL, 5 and 0.2870.38 mm for foldable silicone IOL. 25 Moreover, Fukasaku and Marron ('Accommodation' video presented at the XVIth Congress of the European Society of Cataract & Refractive Surgeons, Nice, France, September 1998), using ultrasound biomicroscopy, showed that the IOL moves anteriorly by a mean of 0.32 mm during near vision; whereas Lesiewska-Junk H and Kahuzny J showed a mean shift of 0.42 mm without any medication. 7 However, these studies have not correlated the OS (axial IOL movement) with the anterior capsule Figure 5 Representative photograph of an eye with practically no cover in group III (total off).…”

Section: Discussionmentioning

confidence: 99%

Anterior capsule cover and axial movement of intraocular lens

Nanavaty

Raj

Vasavada

et al. 2007

Eye

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Purpose To measure optic shift (OS) of a single piece monofocal intraocular lens (IOL) with varying relationships between anterior capsule cover and IOL optic. Methods This is a prospective randomized masked study of 150 eyes undergoing phacoemulsification. Eyes received either option: 360 o total capsule cover (group I); partial cover (group II); or no cover (group III). OS was calculated as difference in anterior chamber depth after administration of cyclopentolate 1% and pilocarpine 2% on IOLMaster s at separate visits at 6 months follow-up. Subsequently, using retro-illumination photographs, percentage area of capsule cover was calculated. OS within and between groups I and II was analyzed. The impact of one quartile change in area of capsule cover on percentage change in OS was measured for both groups. Unpaired t-test, correlation, and regression were applied. Results In groups I, II, and III, mean age of patients was 56.6876.38, 57.0977.34, 59.1576.35 years, respectively; mean OS (mm) was 1.2570.28, 1.2070.24; 0.9570.26 (P ¼ 0.013), respectively; and percentage area of capsule cover (%) was 47.35710.48, 33.83710.11, 0.1670.13 (P ¼ 0.001), respectively. Mean percentage area of capsule cover in group I vs group II was significant (P ¼ 0.001). OS was 1.2270.26 mm in groups I and II (combined) vs 0.9570.26 mm in group III (P ¼ 0.004, (0.06, 0.33)). OS in group I vs group II was not significant (P ¼ 0.46). Correlation coefficient was r ¼ 0.38 (Po0.001). With every increment on quartile (a quartile is any of the three values which divide the sorted data set into four equal parts, so that each part represents one-fourth of the sample or population) class of area of capsule cover the OS increased by 0.12 mm. ConclusionThe OS differed significantly between total and partial cover groups combined vs no cover group.

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Pseudoaccommodation: BioComFoldversus a foldable silicone intraocular lens

Abstract: The design of the BioComFold IOL allowed greater forward optic shifts along the anteroposterior axis during the effort to accommodate. Nevertheless, this shift was not correlated with a significantly greater pseudoaccommodation amplitude.

Cited by 59 publications

References 20 publications

Accommodating intraocular lenses: a critical review of present and future concepts

Accommodating intraocular lenses: a critical review of present and future concepts

Prospective randomised double-masked trial of bilateral multifocal, bifocal or monofocal intraocular lenses

Anterior capsule cover and axial movement of intraocular lens

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