2019
DOI: 10.1101/860650
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pSpatiocyte: a high-performance simulator for intracellular reaction-diffusion systems

Abstract: Background: Studies using quantitative experimental methods have shown that intracellular spatial distribution of molecules plays a central role in many cellular systems. Spatially resolved computer simulations can integrate quantitative data from these experiments to construct physically accurate models of the systems. Although computationally expensive, microscopic resolution reaction-diffusion simulators, such as Spatiocyte can directly capture intracellular effects comprising diffusion-limited reactions an… Show more

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