Psychic Effects of ACTH and Cortisone

Goolker, Paul; Schein, Joseph

doi:10.1097/00006842-195311000-00004

Cited by 81 publications

(14 citation statements)

References 19 publications

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“…Thus, it is possible that either long-term or repeated exposure to glucocorticoids is necessary to elicit pleasurable effects or modulate the subjective effects of psychostimulants. Among the observations that led to the present study were clinical reports that long-term treatment with hydrocortisone elicits feelings of well-being and euphoria (Taylor et al 1950;Rome and Braceland 1952;Fox and Gifford 1953;Goolker and Schein 1953;Rees 1953). Indeed, it has been suggested that this euphoria may contribute to the therapeutic response, independent of the ability of the drug to relieve other disease symptoms (Hollender 1952;Ling et al 1981).…”

Section: Discussionmentioning

confidence: 76%

“…Administration of hydrocortisone in clinical settings has been reported to initially produce mood changes including euphoria, feelings of well being, and increased alertness (Taylor et al 1950;Hollender 1952;Rome and Braceland 1952;Fox and Gifford 1953;Goolker and Schein 1953;Rees 1953;Ling et al 1981). Occasionally, hydrocortisone can also induce extreme acute psychiatric reactions including psychosis, paranoia, and mania (Brody 1952;Rome and Braceland 1952;Glaser 1953;Hall et al 1979;Ling et al 1981).…”

Section: Introductionmentioning

confidence: 99%

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Acute hydrocortisone administration does not affect subjective responses to d-amphetamine in humans

2000

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Section: Discussionmentioning

confidence: 76%

Section: Introductionmentioning

confidence: 99%

Acute hydrocortisone administration does not affect subjective responses to d-amphetamine in humans

2000

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“…Truelove and Witts (111) have reported that ACTH produces psychiatric sequelae. Disturbances may appear within 6-7 h after initial therapy (112) or after prolonged administration.…”

Section: Corticosteroidsmentioning

confidence: 99%

Drug-Induced Mood Disorders

Ananth¹,

Ghadirian²

1980

Int Pharmacopsychiatry

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Various drugs including antihypertensives, anxiolytics, antibiotics, antidepressants, corticosteroids, choline, indomethacin, levodopa, metronidazole, neuroleptics, oral contraceptives, sulphonamides and physostigmine have been reported to produce depression as a side effect. Clinically, these drug-induced depressions may go unnoticed and thus create therapeutic problems. Although causal relationship is difficult to establish, depression occurring during the course of drug treatment needs an evaluation of all the medications that the patient has been receiving. We believe that postpsychotic depressions include three types of depression: pendular depression — primarily disease related; chronic depression - primarily environment related, and amine-depletion depression - drug related. Thus, drug-induced depressions constitute a subgroup of postpsychotic depression. Clinically, it is essential to carefully monitor patients receiving drugs known to produce depression. Thus, prompt recognition of the drug-induced depressions may assist in initiating proper therapeutic measures.

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“…Many studies report psychiatric abnormalities in over 25% of cases of systemic lupus erythematosus (1)(2)(3)(4)(5)(6)(7)14), and the figure is over 50% in several of these studies d-5).…”

Section: Frequencymentioning

confidence: 99%

“…A relationship between systemic lupus erythematosus and coincident psychiatric symptoms has been described in the professional literature over the past 20 years (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12). Nevertheless, uncertainty remains concerning the frequency, form and origin of these psychiatric symptoms.…”

mentioning

confidence: 99%

The Study of the Psychiatric Symptoms of Systemic Lupus Erythematosus

Gurland¹,

Ganz²,

Fleiss³

et al. 1972

Psychosomatic Medicine

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This paper critically reviews studies of psychiatric symptoms in systemic lupus erythematosus. Reported findings vary by chronologic order of publication, clinical orientation of the author, mode of selecting cases and method of examination. This variation in findings reflects errors of method, the most common of which are biased selection of subjects, lack of comparison groups, unreliable recording of observations on the patient and inconsistent presentation of data. Suggestions are made for reducing these errors, including the use of structured interviews and matched comparison groups.A relationship between systemic lupus erythematosus and coincident psychiatric symptoms has been described in the professional literature over the past 20 years (1-12). Nevertheless, uncertainty remains concerning the frequency, form and origin of these psychiatric symptoms.Important theoretic and practical issues wait upon proof that psychiatric symptoms in systemic lupus erythematosus are unusually frequent or of a distinctive form. If psychiatric symptoms are particularly common in systemic lupus erythematosus then their relief is of special concern. Not only are psychiatric symptoms distressing to the patient, but they may impair his ability to cooperate in the treatment of his physical condition. Furthermore, if the form or

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Psychic Effects of ACTH and Cortisone

Cited by 81 publications

References 19 publications

Acute hydrocortisone administration does not affect subjective responses to d-amphetamine in humans

Acute hydrocortisone administration does not affect subjective responses to d-amphetamine in humans

Drug-Induced Mood Disorders

The Study of the Psychiatric Symptoms of Systemic Lupus Erythematosus

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