Psychological distress and changes in the activity of systemic lupus erythematosus

Ward, Michael M.; Marx, A S; Barry, Nouhoun

doi:10.1093/rheumatology/41.2.184

Cited by 61 publications

(63 citation statements)

References 15 publications

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“…17 Other studies show similarity to the results of this research with respect to mean age at the time of diagnosis. 2,16,[18][19][20]24 The diagnosis of SLE is always a nuisance, 21 leaving young women anxious because it occurs in a productive and crucial phase of their life, a time to stabilize their relationships, constitute a family, or choose a career. The author's argument quoted previously is consistent with the results of this study, as the SLE patients were on average 34 years old, but at the time of SLE diagnosis they were on average six years younger.…”

Section: Discussionmentioning

confidence: 99%

Qualidade de vida relacionada à saúde em pacientes com lúpus eritematoso sistêmico no Centro-Oeste do Brasil

Reis¹,

Costa²

2010

Rev. Bras. Reumatol.

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Introduction/Objective: Evaluate the quality of life (QOL) of women with systemic lupus erythematosus (SLE) and the association between QOL domains, measured by the World Health Organization Quality of Life Group (WHOQOL-100) assessment instrument, and disease activity. Patients and Methods: A cross-sectional analytic study involving 95 patients with SLE, according to the American College of Rheumatology (ACR) criteria, aged 20-49 years, attended at the University Center of Universidade Federal de Mato Grosso do Sul, Campo Grande, MS. We used the following instruments: demographic and clinical data collection form and WHOQOL-100 instrument. Evaluation of disease activity was performed by SLEDAI. On statistical analysis, we applied Student's t-test, ANOVA, and Pearson's correlation. Results: Group-case: 79 female with mild to moderate SLE activity (SLEDAI = 1-10) and severe activity (SLEDAI ≥ 11). Control group: 16 female with inactive SLE (SLEDAI = 0). All domains of WHOQOL-100 proved to be affected, with significant difference (P < 0.005) between the case and control groups in which there was a better perception of QOL in the domain Spirituality and worst perception of QOL in the domain Environment. When confronting QOL domains with education, we detected a significant difference (P < 0.05) in the Physical, Psychological, Level of independence, and Environment domains. The comparison between QOL and disease activity was significant (P < 0.005) in three domains: Physical, Psychological, and Environment. Conclusion: SLE with intense activity determines a worse QOL condition than inactive SLE. The assessment of QOL enables the knowledge of disease and treatment impact in a contextualized way, which can render more appropriate and more comprehensive interventions.

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Section: Discussionmentioning

confidence: 99%

Qualidade de vida relacionada à saúde em pacientes com lúpus eritematoso sistêmico no Centro-Oeste do Brasil

Reis¹,

Costa²

2010

Rev. Bras. Reumatol.

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“…Estes dados vão de encontro a diversos estudos que evidenciam que a morbilidade psicológica está correlacionada positivamente com a actividade da doença (Bachen, 2006;Bae et al, 2001;Ishikura et al, 2001;Lim & Boey, 1991;Ward, Marx & Barry, 2002;Yoko et al, 2002).…”

Section: Quadro 1 Estrutura Factorial Do Fadigue Severity Scale (Fss)unclassified

Severe Fatigue in Patients With Systemic Lupus Erythematosus: A Study on the Psychometric Properties of the Severity Fatigue Scale

Pereira¹,

Duarte²

2010

Psic., Saúde & Doença

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RESUMO:O principal objectivo deste estudo foi realizar a adaptação da Escala da Intensidade da Fadiga (Krupp et al., 1989), que visa avaliar a percepção do nível de fadiga em doentes com Lúpus Eritematoso Sistémico (LES). Os resultados, numa amostra de 104 doentes com LES, ao nível da análise factorial revelaram que os itens da versão original se organizam exactamente num único factor, de acordo com o modelo original. Em termos de fidelidade, o coeficiente encontrado foi .96 indicando uma elevada consistência interna dos itens tal como verificado na versão original que foi de .88. Deste modo, a Escala da Intensidade da Fadiga apresenta boas qualidades psicométricas para ser utilizada como medida de avaliação da percepção da fadiga na população portuguesa de doentes com Lúpus Eritematoso Sistémico. Relativamente à validade de constructo, os resultados revelam que quanto mais intensa a fadiga percepcionada pelos doentes com LES, pior a qualidade de vida em todos os domínios (físico, psicológico, relações sociais e meio ambiente) e maior a sintomatologia depressiva e ansiosa apresentada. Palavras-chave: Fadiga Intensa, Lúpus Eritematoso Sistémico, Morbilidade Psicológica, Qualidade de Vida. _________________________________________________________________________________________________________________________________ SEVERE FATIGUE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: A STUDY ON THE PSYCHOMETRIC PROPERTIES OF THE SEVERITY FATIGUE SCALE ABSTRACT:The main purpose of this study was the adaptation of the Fatigue Severity Scale (Krupp et al., 1989), which was designed to assess the perception of fatigue levels in patients with Systemic Lupus Erythematosus (SLE). Using a sample of 104 patients with SLE, the results showed that the Fatigue Severity Scale had a fidelity coefficient of .96, which indicates a high internal consistency of the items, like the original version (.88). The factor analysis showed the items, in the adapted version, to be organized in one factor only, as it happens in the original version. Thus, the Fatigue Severity Scale has good psychometric qualities that allow its use as an assessment tool in the evaluation the perception of fatigue in the Portuguese population of patients with Systemic Lupus Erythematosus. In terms of construct validity results showed, in patients with SLE, higher perceived fatigue to be associated with low quality of life in every domain (physical, psychological, social relationships and environment) and more depressive and anxiety symptoms.

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“…Tench et al (2000) have suggested that myalgia and arthralgia related to lupus may disturb sleep, resulting in daytime fatigue. Increased levels of anxiety and depression are also associated with increased SLErelated fatigue (Ward 2002).…”

Section: Case Study: Fibromyalgia In Slementioning

confidence: 99%

Clinical implications of neuropsychiatric systemic lupus erythematosus

Mak¹,

Ho²,

Lau³

2009

Adv. psychiatr. treat

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SummarySystemic lupus erythematosus (SLE) is a disorder which can affect the central nervous system and result in a broad range of psychiatric syndromes such as psychosis, mood disorders, acute confusion and cognitive dysfunction. Despite the robust nomenclature of neuropsychiatric SLE (NPSLE), psychiatric syndromes in patients are often non-specific and may be secondary to concurrent non-SLE-related conditions and complications of medical therapies. Although the exact immunopathological mechanism for psychiatric presentation remains elusive, prompt exclusion of other factors contributing to the psychiatric symptoms coupled with effective assessment strategies and management with immunosuppression and psychiatric therapy are imperative. Psychiatrists and rheumatologists must work in close liaison to identify, treat and prognosticate patients with psychiatric syndromes in order to improve their quality of life, vocational aptitude and, ultimately, survival.

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Psychological distress and changes in the activity of systemic lupus erythematosus

Abstract: Depression and anxiety scores parallel changes in patients' assessments of the activity of their SLE. We found no evidence to support the hypothesis that psychological distress causes increased SLE activity.

Cited by 61 publications

References 15 publications

Qualidade de vida relacionada à saúde em pacientes com lúpus eritematoso sistêmico no Centro-Oeste do Brasil

Qualidade de vida relacionada à saúde em pacientes com lúpus eritematoso sistêmico no Centro-Oeste do Brasil

Severe Fatigue in Patients With Systemic Lupus Erythematosus: A Study on the Psychometric Properties of the Severity Fatigue Scale

Clinical implications of neuropsychiatric systemic lupus erythematosus

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