Psychosocial burden differences between women of reproductive age and menopausal age due to abnormal Pap smear: A pilot study of the East Coast of Malaysia

Sheikh, Shabbir Ahmad; Mansor, Mardiana; Haque, Mainul

doi:10.4103/2045-080x.186174

Cited by 3 publications

(1 citation statement)

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“…If the cytology reveals abnormal or atypical morphology of the cervix, colposcopy or colposcopic guided excisional biopsy is done. [7][8][9] Initially the Pap smear interpretation was subjective and there is high inter-observer variation. To minimize this, a group of clinician and cytopathologists introduced The Bethesda System for Reporting Cervical Cytopathology (TBSRCC).…”

Section: Introductionmentioning

confidence: 99%

Spectrum of Pap smear cytology according to The Bethesda System 2014

Gupta,

Garg,

Mohan

et al. 2023

JDPO

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Carcinoma of cervix is one of the leading cause of mortality in women across the world. Papanicolaou smear is a valuable screening tool for the neoplastic lesions of cervix. Present study was carried out to do clinicocytological correlation of cervical lesions and to find out the spectrum of cervical lesions in study population. An observational study was conducted at Pathology department in Muzaffarnagar Medical College, Muzaffarnagar. Total 1,017 females were enrolled, scrape smears from the cervix were taken and processed using Papanicolaou's method of staining. These stained smears were examined under microscope and classified according to latest The Bethesda System 2014. Out of 1017 cases, 84.9% (863) smears were classified satisfactory according to 2014 The Bethesda System. Majority of cases (350 cases, 40.5%) belonged to age group of 31-40 years. NILM was the most common cytological finding seen in 340 females (39.3%). The epithelial abnormalities including Atypical Squamous Cells (ASCUS, ASC-H), Squamous Intraepithelial Lesion (LSIL, HSIL) and Squamous Cell Carcinoma were seen in 3.2% of total cases. LSIL found in 1.3% cases and HSIL formed 1.0%. Single case of SCC was detected. Cervical epithelial abnormalities are common in Indian females. Pap smear is the most convenient and OPD test to detect epithelial abnormalities in early phase. Awareness regarding the Pap screening should be encouraged to lessen the morbidity and mortality caused by Carcinoma Cervix.

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Section: Introductionmentioning

confidence: 99%

Spectrum of Pap smear cytology according to The Bethesda System 2014

Gupta,

Garg,

Mohan

et al. 2023

JDPO

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Menopause in adult women with human papillomavirus: health-related quality of life and determinants

Calvo-Torres,

Rejas,

Ramírez-Mena

et al. 2024

Menopause

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Objective Human papillomavirus (HPV) infection and menopause entail a considerable impairment in health-related quality of life (HRQoL). The objective of the present study was to analyze the impact of the menopause status on HRQoL in women with HPV infection. Methods A cross-sectional, nationwide, multicenter sample of women with HPV infection was conducted throughout clinics of gynecology representative of the Spanish population with regard to age, geographic density, and autonomous regions. Demographic and clinical characteristics and the specific HPV-QoL questionnaire score with its domains were compared according to reproductive status: premenopausal and peri-/postmenopausal. Correlation with other validated patient-reported outcomes measurements was also tested, including General Health Questionnaire-12 (GHQ-12), Female Sexual Function Index (FSFI), and Hospital Anxiety and Depression Scale (HADS). Results A sample of 1,016 noninstitutionalized women, aged 18‐80 y, was recorded, 191 (18.8%) peri-/postmenopausal and 825 (81.2%) premenopausal. Total HPV-QoL scoring was significantly lower in peri-/postmenopausal (38.8, 95% CI [35.2-42.4]) compared to premenopausal (46.4, 95% CI [45.0‐47.8]) women, and also in every domain of the scale (P < 0.05), except in social well-being and health domains, with a small effect size of 0.39. In women with sexual dysfunction according to FSFI, adjusted total scoring and domains sexuality, general well-being, and psychological well-being scored significantly higher in premenopause women (P < 0.01), although the magnitude of differences were of small to moderate size. Conclusions HRQoL was impaired during menopause in women with HPV infection according to HPV-QoL questionnaire. The sexuality domain was the most differentiating dimension between these populations.

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