Pterin-based highly selective, ratiometric, and sensitive ‘naked-eye’ sensor for acetate

Synthesis, Redox and Spectroscopic Properties of Pterin of Molybdenum Cofactors

“…Pterin molecules typically exhibit fluorescence and substituting with various functional groups on the pterin can alter the emission energy. This useful property of pterins can see them utilized as fluorophores [ 56 , 57 ] and easily detected as biomarkers for viral infection, inflammation and cancer [ 58 ]. It was also reported that the fluorescence of red blood cells in tunicate, Cnemidocarpa irene, can be attributed to a pterin derivative [ 59 ].…”

Fluorogenic and chromogenic detection of biologically important fluoride anion in aqueous media with a fluorescein-linked hydrogen-bonding receptor via “off–on” approach

“…The binding constant and the detection limit of fluoride anion were 2.2 9 10 4 M -1 and 6.3 9 10 -10 mol/L respectively. Notably, the LOD (low detection limit) was significantly lower than that of most reported F -indicators [18][19][20][21][22]. 1 HNMR titration of L with fluoride 1 HNMR titrations were performed to precisely study the binding mechanism between L and F -.…”

“…Fluorescein and rhodamine derivatives have been extensively employed to construct fluorescent probes for ions and biomolecules such as calcium ion and cyanide [13][14][15][16][17]. Colorimetric receptors are especially attractive, which allow for the naked-eye detection without the use of expensive equipment [18][19][20][21][22]. The preferable binding with fluoride anion via directional hydrogen bonding sites shows reversible and fast response for fluoride anion, which is favorable for the real-time and on-site applicability.…”

Exploring the scope of DBU-promoted amidations of 7-methoxycarbonylpterin

“…In addition to pteridine derivatives being used as inhibitors of dihydrofolate reductase and dihydropteroate synthase, pterins have been a useful scaffold in the development of inhibitors of ricin [3,4], methionine synthase [5], nitric oxide synthase [6], shigella [7], and aldose reductase [8], as well as for treatment of leishman-iosis [9]. In addition to their therapeutic potential, pterin derivatives have been an attractive scaffold in the field of supramolecular chemistry, due to their well-defined donor/acceptor hydrogen-bonding arrays [10,11].…”