Ptyalism and Partial Hydatidiform Mole Associated with a Normal Term Male Fetus

Abstract

The case is described of a subfertile woman whose only successful pregnancy was complicated by the unusual combination of ptyalism and a partial hydatidiform mole. Review after delivery of an ultrasonic scan taken at 17 weeks showed the mole to be present at that time. A normal male child was delivered at term. It is concluded that there was no causal relationship between these 2 conditions.

Risk factors for gestational trophoblastic neoplasia development of singleton normal fetus with partial hydatidiform mole pregnancy: A retrospective cohort and literature review

“…From January 2005 to December 2017, 8 (1.15%) cases of singleton normal fetus with PHM pregnancy were diagnosed from 698 patients with hydatidiform moles at West China Second University Hospital of Sichuan University (Figure 1). Studies in English language composed of 28 cases published during 1975–2021 that displayed information on clinical presentation, pregnancy outcomes, and GTN development were included in the review 6–8,10–28 (Figure 1). Among 36 patients, the median age was 26.0 (17.0–38.0) years, and 30 (83.3%) were aged 20–34 years.…”

Mola parcial con feto vivo, complicado con restricción de crecimiento intrauterino y preeclamsia severa. Reporte de caso y revisión de la literatura

“…Sitio del estudio: un total de 5 estudios fueron realizados en Estados Unidos (13,(20)(21)(22)(23), tres en India (24)(25)(26), dos en México (27,28), dos en China (29,30) (29,32,38,41), de 28 a 37 semanas 6 casos (24,27,36,37,39) y 37 semanas o más en 4 casos (13,26,31). El método de diagnóstico fue ultrasonido prenatal en 21 casos (20,21,(23)(24)(25)27,28,30,(32)(33)(34)(35)37,40,(42)(43), y en el alumbramiento o por patología, 10 casos (13,26,29,31,36,38,39,41,43). Se ofreció terminación del embarazo en 4 casos (20,23).…”

“…El método de diagnóstico fue ultrasonido prenatal en 21 casos (20,21,(23)(24)(25)27,28,30,(32)(33)(34)(35)37,40,(42)(43), y en el alumbramiento o por patología, 10 casos (13,26,29,31,36,38,39,41,43). Se ofreció terminación del embarazo en 4 casos (20,23).…”

“…La edad gestacional al momento de la terminación del embarazo osciló entre las 15 y las 40 semanas: de 22 semanas o menos, 9 casos (20,22,23,28,40); de 23 a 27 semanas, 4 casos (29,32,34,38); de 28 a 37 semanas, 13 casos (21,24-25-26-28,30,33,36,39,41,42-43) y de 38 a 42 semanas, 5 casos (13,26,31,35,37). Respecto al tipo de parto: parto por cesárea, 12 casos (8,21,26,27,(30)(31)(32)(33)(34)39,42,43), parto vaginal, 10 casos (13,25,28,29,(35)(36)(37)41,42).…”

“…Resultado fetal: 9 casos terminaron en aborto (20,22,23,28,40); 8 casos presentaron óbito o muerte neonatal temprana (24,28,29,32,34,38,39,41). Restricción de crecimiento intrauterino, 6 casos (24,25,27,37,39,43); malformaciones fetales, 2 casos; un caso de Dandy Walker (26) y un caso con mielomeningocele (38).…”