Pubertal growth in height, sitting height and leg length in achondroplasia

Cole, Tim J.; Pino, Mariana del; Adamo, Paula; Fano, Virginia

doi:10.1080/03014460.2021.1883109

Cited by 6 publications

(4 citation statements)

References 18 publications

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“…Furthermore, sarcopenia linked to menopausal hormonal deficiencies in estrogen presents adverse impacts related to musculoskeletal function in daily activities such as walking [31]. A higher proportion of women with obesity compared to men can further reduce mobility [32], and height differences between females and males is important to note for how stature may have influenced walking speed [33,34]. These findings pose health implications, suggesting women are a target group for the prevention and treatment of slow gait speed.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Trends of Slow Gait Speed in the United States

Stover,

Andrew,

Batesole

et al. 2023

Geriatrics

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Gait speed is a simple, effective indicator of age-related disease and disability. We sought to examine the prevalence and trends of slow gait speed in older Americans. Our unweighted analytic sample included 12,427 adults aged ≥ 65 years from the 2006–2016 waves of the Health and Retirement Study. Gait speed was measured in participant residences. Persons with gait speed < 0.8 or <0.6 m/s were slow. Sample weights were used to generate nationally representative estimates. The overall estimated prevalence of slow gait speed with the <0.8 m/s cut-point was 48.6% (95% confidence interval (CI): 47.4–49.8) in the 2006–2008 waves yet was 45.7% (CI: 44.3–47.1) in the 2014–2016 waves, but this downward trend was not statistically significant (p = 0.06). The estimated prevalence of slowness with the <0.6 m/s cut-point was 21.3% (CI: 20.4–22.3) for the 2006–2008 waves, 18.5% (CI: 17.5–19.4) for the 2010–2012 waves, and 19.2% (CI: 18.2–20.2) for the 2014–2016 waves, but there were again no significant trends (p = 0.61). Our findings showed that the estimated prevalence of slow gait speed in older Americans is pronounced, and different cut-points largely inform how slowness is categorized. Continued surveillance of slowness over time will help guide screening for disablement and identify sub-populations at greatest risk for targeted interventions.

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Section: Discussionmentioning

confidence: 99%

Prevalence and Trends of Slow Gait Speed in the United States

Stover,

Andrew,

Batesole

et al. 2023

Geriatrics

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“…The height is approximately 5.00 SD below the median compared non-achondroplastic populations with a mean adult height of approximately -6 SD [8,10,11,91].Thus, the curves are similar in shape but lesser in magnitude in comparison to the general population in both periods [34,90]. Besides, 72% of that small growth peak is caused by the peak of trunk length [90,92,93].…”

Section: Quality Of Life Of the Patient And Familiesmentioning

confidence: 86%

Achondroplasia in Latin America: practical recommendations for the multidisciplinary care of pediatric patients

et al. 2022

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Background Achondroplasia is the most common bone dysplasia associated with disproportionate short stature, and other comorbidities, such as foramen magnum stenosis, thoracolumbar kyphosis, lumbar hyperlordosis, genu varum and spinal compression. Additionally, patients affected with this condition have higher frequency of sleep disorders, ear infections, hearing loss and slowed development milestones. Considering these clinical features, we aimed to summarize the regional experts’ recommendations for the multidisciplinary management of patients with achondroplasia in Latin America, a vast geographic territory with multicultural characteristics and with socio-economical differences of developing countries. Methods Latin American experts (from Argentina, Brazil, Chile and Colombia) particiáted of an Advisory Board meeting (October 2019), and had a structured discussion how patients with achondroplasia are followed in their healthcare centers and punctuated gaps and opportunities for regional improvement in the management of achondroplasia. Results Practical recommendations have been established for genetic counselling, prenatal diagnosis and planning of delivery in patients with achondroplasia. An outline of strategies was added as follow-up guidelines to specialists according to patient developmental phases, amongst them neurologic, orthopedic, otorhinolaryngologic, nutritional and anthropometric aspects, and related to development milestones. Additionally, the role of physical therapy, physical activity, phonoaudiology and other care related to the quality of life of patients and their families were discussed. Preoperative recommendations to patients with achondroplasia were also included. Conclusions This study summarized the main expert recommendations for the health care professionals management of achondroplasia in Latin America, reinforcing that achondroplasia-associated comorbidities are not limited to orthopedic concerns.

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“…The assessment of their respective levels and proportional relationships throughout the growth process aids in the identification of conditions associated with abnormal height growth-related diseases. [3,4] This study involved the analysis of data obtained from the physical growth census of elementary school students aged 6 to 12 years in Tianyuan District, Zhuzhou City. The collected data were then compared with national standards to elucidate the patterns of changes in height and body proportions among children within the specified age range in the district.…”

Section: Introductionmentioning

confidence: 99%

Study of height, sitting height, lower extremity length, and the prevalence of short stature among elementary school students in the Tianyuan District of Zhuzhou City

Tang,

Gong,

et al. 2024

Medicine

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In this study, the height, sitting height, lower extremity length, growth status, and body proportions of elementary school students aged 6 to 12 years in Tianyuan District of Zhuzhou City, China, were analyzed. A total of 41,156 children from 38 elementary schools in the Tianyuan District of Zhuzhou City were selected for height measurement, employing the cluster sampling method. After the cluster data were obtained, the height and sitting height information were extracted, and calculations were performed for lower extremity length, sitting height-to-lower extremity length ratio, and sitting height-to-height ratio. Statistical analysis was conducted using SPSS 23.0 software. The height and sitting height measurements of boys and girls aged 6 to 12 years in Tianyuan District surpassed the 2005 national standard set for 9 cities, while the lower extremities of children within the 7 to 9 age range fell below the national standard. In alignment with the national average, the fitted curve representing height for both boys and girls aged 6 to 12 years in Tianyuan District exhibited an intersection point around 10 to 10.5 years. No discernible distinction was observed in the incidence of short stature, as analyzed through the P3 standard, between the fitted curve for Tianyuan District and the national standard. Moreover, tall children exhibited a significantly lower sitting height-to-height ratio compared to their shorter counterparts. The fitted height curve in Tianyuan District, Zhuzhou City, proves effective in discerning shorter-statured children within the region. Nevertheless, further research is warranted to elucidate the factors contributing to the comparatively shorter lower extremities observed in children from Tianyuan District, Zhuzhou City, in contrast to the national average.

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Pubertal growth in height, sitting height and leg length in achondroplasia

Cited by 6 publications

References 18 publications

Prevalence and Trends of Slow Gait Speed in the United States

Prevalence and Trends of Slow Gait Speed in the United States

Achondroplasia in Latin America: practical recommendations for the multidisciplinary care of pediatric patients

Study of height, sitting height, lower extremity length, and the prevalence of short stature among elementary school students in the Tianyuan District of Zhuzhou City

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