Pulmonary Cryptocococcis followed by Pulmonary Tuberculosis

Riley, Edgar Alsop; Cahan, William G.

doi:10.1164/arrd.1972.106.4.594

Cited by 12 publications

(2 citation statements)

References 10 publications

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“…Another patient developed bronchiolitis obliterans-organizing pneumonia (64). Pulmonary cryptococcosis in the immunocompetent host has occurred as a coinfection with both Mycobacterium tuberculosis (90,228,424) and echinococci (101). In one case, pulmonary tuberculosis developed several years after lung resection for cryptococcosis (424).…”

Section: Lungsmentioning

confidence: 99%

Cryptococcosis in the era of AIDS--100 years after the discovery of Cryptococcus neoformans

1995

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Although Cryptococcus neoformans and cryptococcosis have existed for several millennia, a century has passed since the discovery of this encapsulated yeast and its devastating disease. With the advent of the AIDS pandemic, cryptococcal meningitis has emerged as a leading cause of infectious morbidity and mortality and a frequently life-threatening opportunistic mycosis among patients with AIDS. Both basic and clinical research have accelerated in the 1990s, and this review attempts to highlight some of these advances. The discussion covers recent findings, current concepts, controversies, and unresolved issues related to the ecology and genetics of C. neoformans; the surface structure of the yeast; and the mechanisms of host defense. Regarding cell-mediated immunity, CD4+ T cells are crucial for successful resistance, but CD8+ T cells may also participate significantly in the cytokine-mediated activation of anticryptococcal effector cells. In addition to cell-mediated immunity, monoclonal antibodies to the major capsular polysaccharide, the glucuronoxylomannan, offer some protection in murine models of cryptococcosis. Clinical concepts are presented that relate to the distinctive features of cryptococcosis in patients with AIDS and the diagnosis, treatment, and prevention of cryptococcosis in AIDS patients.

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Section: Lungsmentioning

confidence: 99%

Cryptococcosis in the era of AIDS--100 years after the discovery of Cryptococcus neoformans

1995

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“…However, only a handful of cases of pulmonary cryptococcosis associated with pulmonary tuberculosis have been reported (1)(2)(3)(4)(5). We herein report three cases of tuberculosis and cryptococcosis co-infection in patients treated at Nagasaki University Hospital and also carry out a review of other relevant reports.…”

Section: Introductionmentioning

confidence: 99%

Three Cases of Concurrent Infection with <i>Mycobacterium tuberculosis</i> and <i>Cryptococcus neoformans</i>

et al. 2014

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Impaired cellular-mediated immunity is a known risk factor for both tuberculosis and cryptococcosis. However, pulmonary cryptococcosis associated with pulmonary tuberculosis is rare. We herein describe three cases of concurrent infection with Mycobacterium tuberculosis and Cryptococcus neoformans. All patients had underlying diseases; all three had uncontrolled diabetes mellitus, and other underlying diseases were liver cirrhosis, malignancy, and rheumatoid arthritis requiring long-term steroid use. We also review other relevant reports.

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Pulmonary Cryptococcosis

Cameron

Perfect

1994

Pulmonary Infections and Immunity

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Pulmonary Cryptocococcis followed by Pulmonary Tuberculosis

Cited by 12 publications

References 10 publications

Cryptococcosis in the era of AIDS--100 years after the discovery of Cryptococcus neoformans

Cryptococcosis in the era of AIDS--100 years after the discovery of Cryptococcus neoformans

Three Cases of Concurrent Infection with <i>Mycobacterium tuberculosis</i> and <i>Cryptococcus neoformans</i>

Pulmonary Cryptococcosis

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