Pulmonary Echinococcus in children: A descriptive study in a LMIC

Mfingwana, Lunga; Goussard, Pierre; Wyk, Lizelle Van; Morrison, Julie; Gie, André; Mohammed, Rusha A A; Janson, Jacques; Wagenaar, Riegart; Ismail, Zane; Schubert, Pawel

doi:10.1002/ppul.25854

Cited by 7 publications

(10 citation statements)

References 24 publications

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“…They demonstrated that simple small pulmonary echinococcal lesions could be excised using endostaplers. Mfingwana et al [ 18 ] described a pediatric cohort diagnosed with pulmonary CE and treated with a combination of medical and surgical therapy. In endemic areas of hepatic echinococcosis, laparoscopy should be performed for hepatic cysts that are highly suspected to be CE, as a diagnostic and therapeutic tool.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis and treatment experience of atypical hepatic cystic echinococcosis type 1 at a tertiary center in China

Li,

Zhang,

et al. 2024

World J Gastroenterol

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BACKGROUND Some hydatid cysts of cystic echinococcosis type 1 (CE1) lack well-defined cyst walls or distinctive endocysts, making them difficult to differentiate from simple hepatic cysts. AIM To investigate the diagnostic methods for atypical hepatic CE1 and the clinical efficacy of laparoscopic surgeries. METHODS The clinical data of 93 patients who had a history of visiting endemic areas of CE and were diagnosed with cystic liver lesions for the first time at the People's Hospital of Xinjiang Uygur Autonomous Region (China) from January 2018 to September 2023 were retrospectively analyzed. Clinical diagnoses were made based on findings from serum immunoglobulin tests for echinococcosis, routine abdominal ultrasound, high-frequency ultrasound, abdominal computed tomography (CT) scan, and laparoscopy. Subsequent to the treatments, these patients underwent reexaminations at the outpatient clinic until October 2023. The evaluations included the diagnostic precision of diverse examinations, the efficacy of surgical approaches, and the incidence of CE recurrence. RESULTS All 93 patients were diagnosed with simple hepatic cysts by conventional abdominal ultrasound and abdominal CT scan. Among them, 16 patients were preoperatively diagnosed with atypical CE1, and 77 were diagnosed with simple hepatic cysts by high-frequency ultrasound. All the 16 patients preoperatively diagnosed with atypical CE1 underwent laparoscopy, of whom 14 patients were intraoperatively confirmed to have CE1, which was consistent with the postoperative pathological diagnosis, one patient was diagnosed with a mesothelial cyst of the liver, and the other was diagnosed with a hepatic cyst combined with local infection. Among the 77 patients who were preoperatively diagnosed with simple hepatic cysts, 4 received aspiration sclerotherapy of hepatic cysts, and 19 received laparoscopic fenestration. These patients were intraoperatively diagnosed with simple hepatic cysts. During the follow-up period, none of the 14 patients with CE1 experienced recurrence or implantation of hydatid scolices. One of the 77 patients was finally confirmed to have CE complicated with implantation to the right intercostal space. CONCLUSION Abdominal high-frequency ultrasound can detect CE1 hydatid cysts. The laparoscopic technique serves as a more effective diagnostic and therapeutic tool for CE.

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Section: Discussionmentioning

confidence: 99%

Diagnosis and treatment experience of atypical hepatic cystic echinococcosis type 1 at a tertiary center in China

Li,

Zhang,

et al. 2024

World J Gastroenterol

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“…Preoperative chemotherapy with albendazole or mebendazole is recommended to reduce the risk of secondary echinococcosis after the operation. Initiation of this chemotherapy should begin at least 4 days before the surgical procedure and continue for a duration of at least 1–3 months 3 , 20 , 21 .…”

Section: Discussionmentioning

confidence: 99%

A life-threatening encounter: an uncommon case of ruptured hydatid cyst presenting as anaphylactic shock and respiratory distress in a 12-year-old boy

Vantankhah,

Taqanaki,

Rahmanian

et al. 2023

Annals of Medicine &Amp; Surgery

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Introduction and importance: Although rare, the spontaneous rupture of a lung hydatid cyst or its perforation into the pleural cavity can give rise to an abrupt onset of symptoms, including cough, fever, hemoptysis (coughing up blood), and hypersensitivity reactions, and can ultimately lead to respiratory failure. Case presentation: A 12-year-old boy was brought to the emergency room with a loss of consciousness. Symptoms included tachypnea, fever, low blood pressure, and overall respiratory distress. After resuscitation, a chest X-ray revealed a distinct, well-defined round opacity located in the lower region of the right lung, leading to mediastinal displacement. After confirmation of the disease, the child was hospitalized in the ICU care and consequently underwent surgery. Treatment was successful and there was no recurrence on the follow-up. Clinical discussion: Studies have demonstrated that the right lower lobe of the lung is the most frequently affected area of the lung by hydatid cysts. Symptomatic and complicated hydatid cysts are a rare concept in children, and only a small percentage, are diagnosed in patients younger than 16 years. Surgery remains the preferred treatment for the majority of patients with pulmonary hydatid disease. It is important to note that combined surgery and chemotherapy represents the current gold standard in managing pulmonary hydatid cyst. Conclusion: Although anaphylactic shock caused by a ruptured lung hydatid cyst is rare, it should be taken into consideration by physicians as a differential diagnosis in patients who also have respiratory symptoms, particularly in endemic areas.

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“…Limited number of studies have reported renal involvement in pediatric cases 1–3 . In the study by Mfingwana 1 and colleagues, only two cases with lung involvement additionally had spleen involvement, while no case of renal involvement was observed. At the same time, In the study by Çay 2 and colleagues, only three cases with lung involvement additionally had renal involvement.…”

Section: Figurementioning

confidence: 99%

“…The renal involvement was especially significant in this case. Limited number of studies have reported renal involvement in pediatric cases 1–3 . In the study by Mfingwana 1 and colleagues, only two cases with lung involvement additionally had spleen involvement, while no case of renal involvement was observed.…”

Section: Figurementioning

confidence: 99%

“…We would like to share the 16‐year‐old adolescent case with very demonstrative postero‐anterior chest X‐ray and computed tomography images. The recent case series by Mfingwana 1 and Çay 2 are very beneficial to clinicians for interpretation of the topic. In these studies, the authors described 48 pediatric cases between ages 3–18 with different organ involvement.…”

Section: Figurementioning

confidence: 99%

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