Pulmonary Embolectomy

Sharp, Edward H.

doi:10.1097/00000658-196207000-00001

Cited by 129 publications

(5 citation statements)

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“…8 Later, Sharp performed the first successful pulmonary embolectomy on cardiopulmonary bypass in 1962. 9 In 1991, Meyer et al reported a 20-year experience treating 96 patients with pulmonary embolectomy on cardiopulmonary bypass. 10 Operative mortality was 37.5%.…”

Section: Surgical Pulmonary Embolectomy Comes Full Circlementioning

confidence: 99%

A Brief Historical Perspective on Pulmonary Embolism

Morgan,

Saha

2024

Int J Angiol

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Pulmonary embolism is a major cause of mortality worldwide. In this historical perspective, we aim to provide an overview of the rich medical history surrounding pulmonary embolism. We highlight Virchow's first steps toward understanding the pathophysiology in the 1800s. We see how those insights inspired early attempts at intervention such as surgical pulmonary embolectomy and caval ligation. Those early interventions were refined and ultimately led to the development of inferior vena cava filters, the earliest clinical applications of anticoagulation, and even apparently disparate medical advances such as the successful development of cardiopulmonary bypass. We also see how the diagnosis of pulmonary embolism has evolved from rudimentary monitoring of vitals and symptoms to the development of evermore sophisticated tests such as contrast tomography angiography and echocardiography. Finally, we discuss current approaches to diagnosis, classification, and myriad treatments including anticoagulation, thrombolysis, catheter-directed interventions, surgical embolectomy, and extracorporeal membrane oxygenation guided by Pulmonary Embolism Response Teams.

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Section: Surgical Pulmonary Embolectomy Comes Full Circlementioning

confidence: 99%

A Brief Historical Perspective on Pulmonary Embolism

Morgan,

Saha

2024

Int J Angiol

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“…As a result, anesthesia induction can be hazardous because most anesthetics lead to a loss of adrenergic tone, resulting in a cycle of decreased venous return and perfusion pressure, which, unless intervened on rapidly, may culminate in profound hemodynamic instability and cardiac arrest. 10,26,27,29,30 For example, in a study of 52 patients undergoing emergency pulmonary embolectomy, hemodynamic collapse requiring CPR after anesthesia induction occurred in 19% of patients. 31 In a modern series of 59 patients with high-risk PE, anesthesia induction precipitated the need for CPR in 50% of patients who required preoperative CPR.…”

Section: Anesthesia Considerationsmentioning

confidence: 99%

Surgical Management and Mechanical Circulatory Support in High-Risk Pulmonary Embolisms: Historical Context, Current Status, and Future Directions: A Scientific Statement From the American Heart Association

Goldberg¹,

Giri²,

Kobayashi³

et al. 2023

Circulation

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Acute pulmonary embolism is the third leading cause of cardiovascular death, with most pulmonary embolism–related mortality associated with acute right ventricular failure. Although there has recently been increased clinical attention to acute pulmonary embolism with the adoption of multidisciplinary pulmonary embolism response teams, mortality of patients with pulmonary embolism who present with hemodynamic compromise remains high when current guideline-directed therapy is followed. Because historical data and practice patterns affect current consensus treatment recommendations, surgical embolectomy has largely been relegated to patients who have contraindications to other treatments or when other treatment modalities fail. Despite a selection bias toward patients with greater illness, a growing body of literature describes the safety and efficacy of the surgical management of acute pulmonary embolism, especially in the hemodynamically compromised population. The purpose of this document is to describe modern techniques, strategies, and outcomes of surgical embolectomy and venoarterial extracorporeal membrane oxygenation and to suggest strategies to better understand the role of surgery in the management of pulmonary embolisms.

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“…However, the results continued to be disastrous until Gibbon developed a cardiopulmonary bypass (CPB) in 1953. One incentive for the development of CPB was the poor results of surgical embolectomy, but the first use of CPB in this operation came approximately 10 years later, performed by Cooley in 1961 and Sharp in 1962 [ 25 , 26 ].…”

Section: Surgical Treatmentmentioning

confidence: 99%

Surgical pulmonary embolectomy: state of the art

Zieliński¹,

Dyk²,

Wróbel³

et al. 2023

kitp

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Acute pulmonary embolism is a significant cause of morbidity and mortality. Patients in life-threatening conditions require timely and effective interventions to improve pulmonary perfusion. The indications for surgical embolectomy in the thrombolysis era have been limited. This article discusses surgical techniques and outlines the position of surgical embolectomy concerning other treatment modalities.

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Pulmonary Embolectomy

Cited by 129 publications

References 1 publication

A Brief Historical Perspective on Pulmonary Embolism

A Brief Historical Perspective on Pulmonary Embolism

Surgical Management and Mechanical Circulatory Support in High-Risk Pulmonary Embolisms: Historical Context, Current Status, and Future Directions: A Scientific Statement From the American Heart Association

Surgical pulmonary embolectomy: state of the art

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