Pulmonary embolism on non-stop flights between France and Reunion Island

Paganin, F.; Laurent, Yves; Gaüzère, B. A.; Blanc, P; Roblin, Xavier

doi:10.1016/s0140-6736(96)90659-5

Cited by 28 publications

(15 citation statements)

References 3 publications

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“…3,4 Roughly 100 cases of pulmonary embolism occurring after air travel have been reported during the past three decades. 1,2,[5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] Most of these re-A ports were based on small numbers of patients, included cases of both deep venous thrombosis and pulmonary embolism, or included poorly documented cases. We therefore undertook a more comprehensive evaluation of this association.…”

mentioning

confidence: 99%

Severe Pulmonary Embolism Associated with Air Travel

et al. 2001

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mentioning

confidence: 99%

Severe Pulmonary Embolism Associated with Air Travel

et al. 2001

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“…Dans une série de 182 patients ayant eu une embolie pulmonaire, un vol longcourrier en classe économique avait été trouvé à trois reprises [3]. Une centaine d'observations publiées jusqu'au début des années 2000 ont évoqué la relation entre les voyages et plus particulièrement les voyages en avion et la survenue d'accidents thromboemboliques [4][5][6][7][8].…”

Section: Points Essentielsunclassified

“…De façon similaire, plusieurs auteurs ont observé que les femmes étaient particulièrement concernées par le risque d'accident thromboembolique. Ce chiffre est de l'ordre de 70 % dans la plupart des études [7,32,34]. Il atteint 90 % dans une étude japonaise [37].…”

Section: Identification Des Facteurs De Risque De Survenue D'accidentunclassified

Accidents thromboemboliques et voyages aériens

2012

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“…Advanced age and immobilization further increase the frequency of thrombosis. Venous stasis is associated with impaired fibrinolysis and activation of coagulation [56,57], increased fluid retention, causing swelling in the legs [58] and increased erythropoietin levels [59].…”

Section: Venous Stasismentioning

confidence: 99%

Air Travel-Associated Venous Thromboembolism

Iqbal

Eklöf²,

Töbü³

et al. 2003

Med Princ Pract

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Long-distance air travel is increasing and cases of venous thromboembolism (VTE) following air travel have attracted both considerable public attention and legal claims against airlines. VTE is a common disorder worldwide with a notably high incidence in older individuals. Many biochemical factors that lead to, or accentuate, thrombus formation are associated with increased risk of VTE. These factors include thrombophilia, activated protein C resistance and factor V Leiden, prothrombin gene mutation, antiphospholipid antibodies, protein S and protein C deficiencies, and methylene tetrahydrofolate reductase polymorphism and homocysteinemia. Individual physical characteristics including age, weight and height are significant for personal risk of VTE as are other factors such as use of oral contraceptives in women. In the case of air travel-related venous thrombosis, superimposed upon these individual factors are the environmental factors directly related to air travel. Travel-related factors include stasis associated with prolonged periods of immobility, physiological stresses resulting from exposure to the cabin environment (low humidity and hypoxia) in long-haul flight and other in-flight factors. It is suggested that passenger behavior (movement, avoidance of dehydration and of alcohol) and appropriate pharmacological prophylaxis for high-risk travelers can reduce the likelihood of VTE. Physical prophylaxis (use of compression stockings or in-flight exercise devices) may also be of general benefit to passengers. It is recommended that airlines become more proactive in educating passengers concerning the dangers of VTE and in promoting passenger actions that can reduce risk. Airlines should also work to avoid cramped seating conditions (seat size and pitch) that contribute to prolonged immobility. Governments and regulatory authorities should mandate the provision of adequate seating conditions and a good cabin environment and should support studies that will define risks and determine the efficacy of protocols to minimize dangers of VTE. Increased long-haul air traffic and an aging population suggest that travel-related VTE may present a growing healthcare threat and has highlighted a need for additional biomedical research into the causes and potential solutions to this problem.

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Pulmonary embolism on non-stop flights between France and Reunion Island

Cited by 28 publications

References 3 publications

Severe Pulmonary Embolism Associated with Air Travel

Severe Pulmonary Embolism Associated with Air Travel

Accidents thromboemboliques et voyages aériens

Air Travel-Associated Venous Thromboembolism

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